Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7568141 | 0.93 | RAD52 (0.52) | RAD52HDAC1HDAC6MAPK1ALDH1A1 | |
| SCHEMBL7567208 | 0.92 | HDAC1 (0.43) | RAD52HDAC1HDAC6MAPK1ALDH1A1 | |
| SCHEMBL7567233 | 0.85 | RAD52 (0.40) | RAD52HDAC1HDAC6MAPK1ALDH1A1 | |
| SCHEMBL7565057 | 0.85 | RAD52 (0.54) | RAD52HDAC1HDAC6AOX1TP53 | |
| SCHEMBL7568123 | 0.80 | RAD52 (0.47) | RAD52HDAC1HDAC6MAPTAOX1 | |
| SCHEMBL8413334 | 0.79 | RAD52 (0.54) | RAD52HDAC1HDAC6ALDH1A1HPGD | |
| SCHEMBL7570699 | 0.78 | HDAC1 (0.45) | RAD52HDAC1HDAC6MAPK1ALDH1A1 | |
| SCHEMBL7567419 | 0.78 | RAD52 (0.60) | RAD52MAPTAOX1TP53 | |
| SCHEMBL7567360 | 0.77 | AOX1 (0.51) | RAD52HDAC1HDAC6AOX1KCNH2 | |
| SCHEMBL7567212 | 0.76 | AOX1 (0.49) | RAD52HDAC1HDAC6MAPTAOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934278-B1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LTD (GB) | 2002-09-04 | — | — | EP | claimed |
| EP-0934278-B1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LTD (GB) | 2002-09-04 | — | — | EP | disclosed |
| US-6114332-A | BACTERICIDES | XENOVA LIMITED (GB) | 2000-09-05 | — | — | US | disclosed |