Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 2/20 | 0.60 |
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 7/20 | 0.47 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7565057 | 0.93 | RAD52 (0.54) | RAD52SIGMAR1TMEM97HTTAOX1 | |
| SCHEMBL7567238 | 0.90 | RAD52 (0.47) | RAD52SIGMAR1TMEM97UHRF1HTT | |
| SCHEMBL8413334 | 0.87 | RAD52 (0.54) | RAD52UHRF1TP53 | |
| SCHEMBL7564772 | 0.87 | RAD52 (0.78) | RAD52SIGMAR1TMEM97UHRF1HTT | |
| SCHEMBL7564176 | 0.86 | AOX1 (0.56) | RAD52SIGMAR1TMEM97HTTAOX1 | |
| SCHEMBL7568141 | 0.84 | RAD52 (0.52) | RAD52UHRF1HTTTP53MAPT | |
| SCHEMBL7567212 | 0.84 | AOX1 (0.49) | RAD52SIGMAR1TMEM97UHRF1HTT | |
| SCHEMBL7569011 | 0.82 | RAD52 (0.59) | RAD52SIGMAR1TMEM97UHRF1HTT | |
| SCHEMBL7571933 | 0.81 | SIGMAR1 (0.55) | RAD52SIGMAR1TMEM97AOX1APP | |
| SCHEMBL14440614 | 0.81 | AOX1 (0.51) | RAD52SIGMAR1TMEM97HTTAOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934278-B1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LTD (GB) | 2002-09-04 | — | — | EP | claimed |
| EP-0934278-B1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LTD (GB) | 2002-09-04 | — | — | EP | disclosed |
| US-6114332-A | BACTERICIDES | XENOVA LIMITED (GB) | 2000-09-05 | — | — | US | disclosed |
| EP-0934278-A1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LIMITED (GB) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998017650-A1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LIMITED (GB) | 1998-04-30 | — | — | WO | disclosed |