Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 7/20 | 0.38 |
| ▸ | CA12 | O43570 | 4/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 4/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7160479 | 0.90 | DNM1 (0.46) | TDP1CA1CA12CA9CA2 | |
| SCHEMBL7553791 | 0.90 | DNM1 (0.46) | TDP1CA1CA12CA9CA2 | |
| SCHEMBL5454493 | 0.90 | DNM1 (0.46) | TDP1CA1CA12CA9CA2 | |
| SCHEMBL4666266 | 0.82 | CA1 (0.48) | TDP1CA1CA12CA9CA2 | |
| SCHEMBL7567519 | 0.78 | KDM4E (0.36) | CA1CA12CA2CA14MEN1 | |
| SCHEMBL8654027 | 0.78 | CA1 (0.43) | TDP1CA1CA12CA9CA2 | |
| SCHEMBL11873022 | 0.77 | TDP1 (0.36) | TDP1 | |
| SCHEMBL22761782 | 0.77 | TDP1 (0.40) | TDP1CA1CA12CA9CA2 | |
| SCHEMBL11989255 | 0.76 | MEN1 (0.44) | TDP1CA1CA12CA9CA2 | |
| SCHEMBL5163572 | 0.76 | APP (0.35) | TDP1ALDH1A1LMNATP53MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3183236-A1 | METHOD FOR THE PRODUCTION OF 18F-LABELED ACTIVE ESTERS AND THEIR APPLICATION EXEMPLIFIED BY THE PREPARATION OF A PSMA-SPECIFIC PET-TRACER | Max-Planck-Gesellschaft zur Förderung der Wissenschaften (DE) | 2017-06-28 | — | — | EP | disclosed |
| WO-2016030329-A1 | METHOD FOR THE PRODUCTION OF 18F-LABELED ACTIVE ESTERS AND THEIR APPLICATION EXEMPLIFIED BY THE PREPARATION OF A PSMA-SPECIFIC PET-TRACER | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2016-03-03 | — | — | WO | disclosed |