Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | AR | P10275 | 5/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.33 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11753774 | 0.80 | AR (0.39) | TSHRARCA1CA2DYRK1A | |
| SCHEMBL11870399 | 0.80 | TSHR (0.35) | TSHRARCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL11870455 | 0.79 | TSHR (0.39) | TSHRARCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL11660313 | 0.79 | TSHR (0.39) | TSHRARCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL3148798 | 0.76 | TSHR (0.35) | TSHR | |
| SCHEMBL103847 | 0.76 | AR (0.59) | ARSLC22A12PGR | |
| SCHEMBL179312 | 0.76 | TSHR (0.50) | TSHRARCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL30794742 | 0.76 | AR (0.59) | ARSLC22A12PGR | |
| SCHEMBL11036143 | 0.76 | TSHR (0.35) | TSHR | |
| Hydrochloric Acid SCHEMBL22117993 | 0.74 | AR (0.58) | ARSLC22A12PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362372-B2 | HYDROGENATION OF A TRIFLUOROBENZYLNITRILE BY HYDROGEN IN AN ORGANIC SOLVENT IN THE PRESENCE OF AMMONIA AND A CATALYST COMPRISING A PLATINUM GROUP ELEMENT; EXTREMELY HIGH YIELDS | CENTRAL GLASS COMPANY, LIMITED (JP) | 2002-03-26 | — | — | US | disclosed |
| US-20020007086-A1 | Process for producing trifluoromethylbenzylamines | CENTRAL GLASS COMPANY, LIMITED (JP) | 2002-01-17 | — | — | US | disclosed |
| EP-0120404-B1 | PROCESS FOR PREPARING BENZAL CHLORIDES | BAYER AG (DE) | 1986-02-19 | — | — | EP | disclosed |
| US-4558166-A | REDUCTION OF BENZOTRICHLORIDES IN THE PREESENCE OF METAL SALTS AS CATALYSTS | BAYER AKTIENGESELLSCHAFT (DE) | 1985-12-10 | — | — | US | disclosed |
| EP-0120404-A1 | Process for preparing benzal chlorides | BAYER AG (DE) | 1984-10-03 | — | — | EP | disclosed |
| US-4226783-A | OF SIDE CHAINS OF ELECTRONEGATIVELY SUBSTITUTED AROMATIC COMPOUNDS WITH DICHLORINE MONOXIDE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1980-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020007086-A1 | Process for producing trifluoromethylbenzylamines | IDH1, INMT, TH | TSHR 525/4885AR 3622/4885CYP1A2 202/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.