SCHEMBL3148798

SCHEMBL3148798

O=[C]c1ccccc1C(Cl)(Cl)Cl

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.35
KCNN4 O15554 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL536089 0.76 ALDH1A1 (0.44) TSHR
SCHEMBL11036143 0.76 TSHR (0.35) TSHRKCNN4
SCHEMBL7567533 0.76 TSHR (0.44) TSHR
SCHEMBL96903 0.76 FFAR1 (0.41) TSHR
SCHEMBL9248714 0.74 ALDH1A1 (0.33) TSHR
SCHEMBL17103426 0.73 SLC22A12 (0.32)
SCHEMBL9678618 0.73 KCNN4 (0.32) TSHRKCNN4
SCHEMBL17103315 0.73 SLC22A12 (0.32)
SCHEMBL7292118 0.73 ALDH1A1 (0.32) TSHR
SCHEMBL545083 0.73 TSHR (0.50) TSHRKCNN4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0135348-B1 IMPROVEMENTS IN OR RELATING TO RADIATION SENSITIVE COMPOUNDS VICKERS PLC (GB) 1989-02-15 EP claimed
EP-0041675-B1 4-HALOGEN-5-(TRICHLOROMETHYL-PHENYL)-OXAZOLE DERIVATIVES, PROCESS FOR PREPARING THEM AND RADIATION-SENSITIVE COMPOSITIONS CONTAINING THEM HOECHST AKTIENGESELLSCHAFT (DE) 1985-12-11 EP claimed
EP-0038223-B1 PROCESS FOR THE PREPARATION OF TRIFLUOROMETHYLBENZOYL HALIDES OCCIDENTAL CHEMICAL CORPORATION (US) 1984-08-08 EP claimed
US-9955689-B2 Method for promoting plant growth SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-05-01 US disclosed
US-9894901-B2 Method for promoting plant growth SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-02-20 US disclosed
US-9872493-B2 Method for promoting plant growth SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-01-23 US disclosed
EP-2049471-B1 PROCESS FOR PREPARING A SULPHONIC ACID ANHYDRIDE RHODIA OPERATIONS (FR) 2016-07-13 EP disclosed
US-20150305332-A1 METHOD FOR PROMOTING PLANT GROWTH SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-10-29 US disclosed
US-20150289512-A1 METHOD FOR PROMOTING PLANT GROWTH SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-10-15 US disclosed
US-20150289506-A1 METHOD FOR PROMOTING PLANT GROWTH SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-10-15 US disclosed
US-20150282482-A1 METHOD FOR PROMOTING PLANT GROWTH SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-10-08 US disclosed
EP-2923573-A1 METHOD FOR PROMOTING PLANT GROWTH Sumitomo Chemical Company Limited (JP) 2015-09-30 EP disclosed
CN-104902749-A Method for promoting plant growth SUMITOMO CHEMICAL CO 2015-09-09 CN disclosed
CN-104902750-A Method for promoting plant growth SUMITOMO CHEMICAL CO 2015-09-09 CN disclosed
CN-104902752-A Method for promoting plant growth SUMITOMO CHEMICAL CO 2015-09-09 CN disclosed
CN-104902751-A Method for promoting plant growth SUMITOMO CHEMICAL CO 2015-09-09 CN disclosed
US-8222450-B2 Preparation of sulfonic acid anhydrides Aubervilliers (FR) 2012-07-17 US disclosed
US-20100076221-A1 PREPARATION OF SULFONIC ACID ANHYDRIDES RHODIA OPERATIONS (FR) 2010-03-25 US disclosed
WO-2006024783-A1 METHOD FOR ACYLATING NUCLEOPHILIC COMPOUNDS IN PARTICULAR ANILINES RHODIA CHIMIE (FR) 2006-03-09 WO disclosed
US-4371607-A 4-Halogeno-5-(halogenomethyl-phenyl)-oxazole derivatives, a process for the preparation thereof, and radiation-sensitive compositions containing these derivatives HOECHST AKTIENGESELLSCHAFT (DE) 1983-02-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100076221-A1 PREPARATION OF SULFONIC ACID ANHYDRIDES CA3, CA9, CA6 TSHR 744/4885KCNN4 3120/4885
US-20150289506-A1 METHOD FOR PROMOTING PLANT GROWTH FGF2, BROX, BOLA2; BOLA2B TSHR 1280/4885KCNN4 3951/4885
US-20150305332-A1 METHOD FOR PROMOTING PLANT GROWTH FGF1, BROX, FGF2 TSHR 1528/4885KCNN4 3883/4885
US-20150282482-A1 METHOD FOR PROMOTING PLANT GROWTH BOLA2; BOLA2B, BROX, TET1 TSHR 1132/4885KCNN4 4207/4885
US-20150289512-A1 METHOD FOR PROMOTING PLANT GROWTH FGF1, MKI67, FGF2 TSHR 3362/4885KCNN4 4518/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.