Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7570411 | 0.92 | POLB (0.47) | HTTPOLBALDH1A1KDM4EPKM | |
| SCHEMBL9422806 | 0.82 | HTT (0.56) | HTTPOLBALDH1A1KDM4EHDAC8 | |
| SCHEMBL7575469 | 0.80 | BDKRB1 (0.44) | HTTLTB4R | |
| SCHEMBL7569087 | 0.79 | SELL (0.62) | HTTPOLBALDH1A1KDM4EHDAC3 | |
| SCHEMBL10584504 | 0.79 | POLB (0.57) | HTTPOLBALDH1A1KDM4EHDAC3 | |
| SCHEMBL7569415 | 0.78 | KDM4E (0.60) | HTTPOLBALDH1A1KDM4EHDAC3 | |
| SCHEMBL9422875 | 0.77 | HTT (0.56) | HTTPOLBALDH1A1KDM4EHDAC8 | |
| SCHEMBL7048020 | 0.76 | PLK1 (0.55) | POLBALDH1A1HDAC8L3MBTL1HPGD | |
| SCHEMBL7569237 | 0.75 | HTT (0.54) | HTTPOLBALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL7575179 | 0.75 | HTT (0.54) | HTTPOLBALDH1A1KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0685470-B1 | Benzene derivatives and pharmaceutical composition | KUREHA CHEMICAL IND CO LTD (JP) | 2002-09-11 | — | — | EP | disclosed |