Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 2/20 | 0.44 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 4/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.40 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7570389 | 0.86 | HTT (0.40) | LTB4R2HTTSOAT1LTB4RGSK3A | |
| SCHEMBL7570660 | 0.85 | PTGER1 (0.41) | BDKRB1SOAT1LTB4R | |
| SCHEMBL7570385 | 0.83 | SOAT1 (0.40) | BDKRB1LTB4R2HTTSOAT1GSK3A | |
| SCHEMBL7575457 | 0.83 | SOAT1 (0.40) | BDKRB1LTB4R2HTTSOAT1AGTR1 | |
| SCHEMBL8081241 | 0.80 | BDKRB1 (0.44) | BDKRB1LTB4R2SOAT1AGTR1AGTR2 | |
| SCHEMBL4609709 | 0.80 | LTB4R2 (0.60) | BDKRB1LTB4R2HTT | |
| SCHEMBL7567767 | 0.80 | HTT (0.51) | HTTLTB4R | |
| SCHEMBL9709600 | 0.77 | AGTR1 (0.48) | AGTR1AGTR2 | |
| SCHEMBL7570411 | 0.75 | POLB (0.47) | BDKRB1HTTLTB4R | |
| SCHEMBL9263754 | 0.75 | AGTR1 (0.44) | BDKRB1AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0685470-B1 | Benzene derivatives and pharmaceutical composition | KUREHA CHEMICAL IND CO LTD (JP) | 2002-09-11 | — | — | EP | disclosed |
| EP-0685470-A2 | Benzene derivatives and pharmaceutical composition | Kureha Chemical Industry Co., Ltd. (JP) | 1995-12-06 | — | — | EP | disclosed |