Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CETP | P11597 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SELL | P14151 | 1/20 | 0.43 |
| ▸ | SELP | P16109 | 1/20 | 0.43 |
| ▸ | SELE | P16581 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7569087 | 0.82 | SELL (0.62) | HTTALDH1A1KDM4EPOLBCYP1A2 | |
| SCHEMBL8095271 | 0.79 | HSP90AA1 (0.44) | HTTALDH1A1KDM4EPOLBNPC1 | |
| SCHEMBL10584504 | 0.79 | POLB (0.57) | HTTALDH1A1KDM4EPOLBCYP1A2 | |
| SCHEMBL7575179 | 0.78 | HTT (0.54) | HTTALDH1A1KDM4EPOLBNPC1 | |
| SCHEMBL7569415 | 0.78 | KDM4E (0.60) | HTTALDH1A1KDM4EPOLBNPC1 | |
| SCHEMBL7596213 | 0.77 | ALDH1A1 (0.51) | HTTALDH1A1KDM4EPOLBLMNA | |
| SCHEMBL10978879 | 0.77 | SELL (0.60) | HTTALDH1A1KDM4EPOLBSMN1; SMN2 | |
| SCHEMBL21998687 | 0.77 | KDM4E (0.65) | HTTALDH1A1KDM4EPOLBSMN1; SMN2 | |
| SCHEMBL21998893 | 0.77 | KDM4E (0.65) | HTTALDH1A1KDM4EPOLBSMN1; SMN2 | |
| SCHEMBL21998912 | 0.77 | KDM4E (0.65) | HTTALDH1A1KDM4EPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0685470-B1 | Benzene derivatives and pharmaceutical composition | KUREHA CHEMICAL IND CO LTD (JP) | 2002-09-11 | — | — | EP | disclosed |
| EP-0685470-A2 | Benzene derivatives and pharmaceutical composition | Kureha Chemical Industry Co., Ltd. (JP) | 1995-12-06 | — | — | EP | disclosed |