SCHEMBL7567988

SCHEMBL7567988

C=CCc1ccc([O])c(CC)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.46
PPARG P37231 2/20 0.46
PPARD Q03181 2/20 0.46
PPARA Q07869 1/20 0.46
XDH P47989 1/20 0.46
CYP3A4 P08684 4/20 0.44
MAPT P10636 4/20 0.44
CYP1A2 P05177 1/20 0.44
GABRA1 P14867 7/20 0.44
GABRB2 P47870 7/20 0.44
CNR2 P34972 5/20 0.44
MEN1 O00255 4/20 0.44
KMT2A Q03164 4/20 0.44
GAA P10253 3/20 0.44
CNR1 P21554 2/20 0.44
KDM4E B2RXH2 2/20 0.44
ALDH2 P05091 1/20 0.44
AKR1B1 P15121 1/20 0.44
HPGD P15428 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4452326 0.88 XDH (0.48) ALDH1A1PPARGPPARDPPARAXDH
SCHEMBL10634220 0.87 ALDH1A1 (0.37) ALDH1A1PPARGPPARDPPARAXDH
SCHEMBL12802185 0.84 ALDH1A1 (0.48) ALDH1A1PPARGPPARDPPARAXDH
SCHEMBL7567997 0.79 XDH (0.63) ALDH1A1PPARGPPARDPPARAXDH
SCHEMBL2863264 0.79 TRPA1 (0.44) ALDH1A1MAPTCYP1A2HPGDSMN1; SMN2
SCHEMBL5961687 0.78 ALDH1A1 (0.47) ALDH1A1PPARGPPARDPPARAXDH
SCHEMBL4451593 0.76 XDH (0.48) ALDH1A1PPARGPPARDPPARAXDH
SCHEMBL12802037 0.74 MAPK1 (0.40) ALDH1A1PPARGPPARDPPARAXDH
SCHEMBL1509672 0.74 XDH (0.68) ALDH1A1PPARGPPARDPPARAXDH
SCHEMBL12802199 0.74 MAPK1 (0.40) ALDH1A1PPARGPPARDPPARAXDH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002079753-A2 2-AMINOBENZOXAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF LION BIOSCIENCE AG (DE) 2002-10-10 WO disclosed