Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 4/20 | 0.54 |
| ▸ | CFTR | P13569 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.47 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26930977 | 0.88 | TAS2R14 (0.48) | TAS2R14CFTRMAPTALOX15AKR1B1 | |
| SCHEMBL6141454 | 0.82 | CFTR (0.60) | TAS2R14CFTRMAPTALOX15AKR1B1 | |
| SCHEMBL7592514 | 0.82 | TAS2R14 (0.70) | TAS2R14CFTRMAPTALOX15AKR1B1 | |
| SCHEMBL7029629 | 0.81 | MAPT (0.61) | CFTRMAPTALOX15KDM4EPOLB | |
| SCHEMBL7568048 | 0.81 | MAPT (0.51) | MAPTALOX15KDM4EPOLBATM | |
| SCHEMBL26930895 | 0.81 | CFTR (0.48) | TAS2R14CFTRMAPTAKR1C3AKR1C2 | |
| SCHEMBL7565893 | 0.81 | TAS2R14 (0.54) | TAS2R14CFTRMAPTALOX15AKR1B1 | |
| SCHEMBL6141350 | 0.80 | CFTR (0.64) | TAS2R14CFTRMAPTALOX15AKR1B1 | |
| SCHEMBL6141404 | 0.79 | AKR1C3 (0.77) | TAS2R14CFTRMAPTALOX15AKR1B1 | |
| SCHEMBL26931075 | 0.78 | CFTR (0.48) | TAS2R14CFTRMAPTRXFP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934278-B1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LTD (GB) | 2002-09-04 | — | — | EP | disclosed |
| US-6114332-A | BACTERICIDES | XENOVA LIMITED (GB) | 2000-09-05 | — | — | US | disclosed |