Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.48 |
| ▸ | TSHR | P16473 | 5/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | CFTR | P13569 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19065779 | 0.86 | MAPT (0.79) | MAPTALOX15KDM4EPOLBATM | |
| SCHEMBL7568048 | 0.84 | MAPT (0.51) | MAPTALOX15KDM4EPOLBATM | |
| SCHEMBL30635255 | 0.83 | LMNA (0.57) | MAPTALOX15KDM4EPOLBATM | |
| SCHEMBL121356 | 0.83 | LMNA (0.57) | MAPTALOX15KDM4EPOLBATM | |
| SCHEMBL8892377 | 0.81 | FABP4 (0.61) | MAPTKMT2AHPGDPTGS2LMNA | |
| SCHEMBL26930977 | 0.81 | TAS2R14 (0.48) | MAPTALOX15KDM4EKMT2AHPGD | |
| SCHEMBL7568046 | 0.81 | TAS2R14 (0.54) | MAPTALOX15KDM4EPOLBATM | |
| Benzene SCHEMBL28217563 | 0.81 | TSHR (0.55) | MAPTALOX15KDM4EPOLBATM | |
| SCHEMBL7034926 | 0.80 | MAPT (0.74) | MAPTALOX15KDM4EPOLBATM | |
| SCHEMBL7566527 | 0.79 | MAPT (0.48) | MAPTALOX15KDM4EPOLBATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934277-B1 | PROCESS FOR THE PREPARATION OF N- 2-(DIMETHYLAMINO)ETHYL]ACRIDINE-4-CARBOXAMIDE | XENOVA LTD (GB) | 2003-02-05 | — | — | EP | disclosed |
| EP-0934278-B1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LTD (GB) | 2002-09-04 | — | — | EP | disclosed |
| US-6114332-A | BACTERICIDES | XENOVA LIMITED (GB) | 2000-09-05 | — | — | US | disclosed |
| US-6111109-A | CYCLIZING A 2-(2-ALKYLOXYCARBONYLPHENYL)AMINO-)BENZALDEHYDE BY TREATING WITH A BORON TRIFLUORIDE; NEUTRALIZATION OF THE FORMED SALT; AMIDATION WITH AN 2-N,N-DIALKYLAMINOETHYLAMINE;ANTITUMOR AND -CARCINOGENIC | XENOVA LIMITED (GB) | 2000-08-29 | — | — | US | disclosed |