Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.46 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7029629 | 0.84 | MAPT (0.61) | MAPTALOX15KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL7571570 | 0.81 | MAPT (0.57) | MAPTALOX15KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL7568046 | 0.81 | TAS2R14 (0.54) | MAPTALOX15KDM4EPOLBATM | |
| SCHEMBL15009851 | 0.78 | L3MBTL1 (0.52) | MAPTKDM4EALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL19065779 | 0.78 | MAPT (0.79) | MAPTALOX15KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL17617073 | 0.76 | MAPT (0.76) | MAPTALOX15KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL18587690 | 0.75 | ERN1 (0.50) | MAPTKDM4EALDH1A1RAB9AABCG2 | |
| SCHEMBL28660772 | 0.75 | MAPT (0.69) | MAPTALOX15KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL17291893 | 0.73 | MAPT (0.67) | MAPTALOX15KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL27522854 | 0.73 | ALDH1A1 (0.56) | MAPTALOX15KDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934278-B1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LTD (GB) | 2002-09-04 | — | — | EP | disclosed |
| US-6114332-A | BACTERICIDES | XENOVA LIMITED (GB) | 2000-09-05 | — | — | US | disclosed |