Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 4/20 | 0.61 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.47 |
| ▸ | NQO2 | P16083 | 2/20 | 0.46 |
| ▸ | NAMPT | P43490 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | G6PD | P11413 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8411929 | 0.87 | KDM4E (0.50) | RAD52SMARCA2HPGDKMT2AMEN1 | |
| SCHEMBL7573561 | 0.86 | RAD52 (0.68) | RAD52SMARCA2HPGDNQO2NAMPT | |
| SCHEMBL29634211 | 0.84 | RAD52 (0.85) | RAD52SMARCA2HPGDNQO2UHRF1 | |
| SCHEMBL8224795 | 0.84 | RAD52 (0.85) | RAD52SMARCA2HPGDNQO2UHRF1 | |
| SCHEMBL7570872 | 0.83 | RAD52 (0.51) | RAD52SMARCA2HPGDMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL10866302 | 0.83 | RAD52 (0.87) | RAD52SMARCA2HPGDNQO2KMT2A | |
| SCHEMBL8415079 | 0.82 | RAD52 (0.50) | RAD52SMARCA2HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL7566449 | 0.81 | CYP1A2 (0.51) | RAD52SMARCA2HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL8009925 | 0.80 | HPGD (0.49) | RAD52SMARCA2HPGDKMT2AMEN1 | |
| SCHEMBL7998025 | 0.78 | RAD52 (0.47) | RAD52SMARCA2HPGDNQO2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934278-B1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LTD (GB) | 2002-09-04 | — | — | EP | claimed |