Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | DHODH | Q02127 | 6/20 | 0.45 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | CDC7 | O00311 | 1/20 | 0.40 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | CDK7 | P50613 | 1/20 | 0.40 |
| ▸ | CDK9 | P50750 | 1/20 | 0.40 |
| ▸ | PRKX | P51817 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7568155 | 0.88 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2ADHODHRXFP1 | |
| SCHEMBL27480286 | 0.87 | PARP1 (0.49) | ALDH1A1AOX1GAATSHR | |
| SCHEMBL902623 | 0.82 | ALDH1A1 (0.66) | ALDH1A1MEN1KMT2ADHODHMAPT | |
| SCHEMBL7566766 | 0.82 | MEN1 (0.60) | ALDH1A1MEN1KMT2AAOX1 | |
| SCHEMBL7575249 | 0.82 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2ADHODHAOX1 | |
| SCHEMBL7569493 | 0.82 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2ADHODHAOX1 | |
| SCHEMBL7569359 | 0.81 | ALDH1A1 (0.51) | ALDH1A1DHODH | |
| SCHEMBL7566734 | 0.78 | KDM4E (0.51) | ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL7030651 | 0.78 | MEN1 (0.53) | ALDH1A1MEN1KMT2AAOX1RXFP1 | |
| SCHEMBL7572783 | 0.78 | ALDH1A1 (0.45) | ALDH1A1MEN1KMT2ADHODHAOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1116285-C | Bis(acridinecarboxamide) and Bis(phenazinecarboxamide) as antitumour agents | XENOVA LTD (GB) | 2003-07-30 | — | — | CN | disclosed |
| EP-0934278-B1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LTD (GB) | 2002-09-04 | — | — | EP | disclosed |
| US-6114332-A | BACTERICIDES | XENOVA LIMITED (GB) | 2000-09-05 | — | — | US | disclosed |
| CN-1240430-A | Bis(acridinecarboxamide) and Bis(phenazinecarboxamide) as antitumour agents | XENOVA LTD (GB) | 2000-01-05 | — | — | CN | disclosed |