Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | DHODH | Q02127 | 8/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | ACMSD | Q8TDX5 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | HNF4A | P41235 | 2/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.45 |
| ▸ | DHFR | P00374 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27450141 | 0.89 | PARP1 (0.64) | ALDH1A1DHODHPARP1BACE1 | |
| SCHEMBL902623 | 0.84 | ALDH1A1 (0.66) | ALDH1A1DHODHTP53CYP1A2HSD17B10 | |
| SCHEMBL7568063 | 0.81 | ALDH1A1 (0.49) | ALDH1A1DHODH | |
| SCHEMBL7566766 | 0.81 | MEN1 (0.60) | ALDH1A1PARP1HSD17B10 | |
| SCHEMBL7569493 | 0.81 | ALDH1A1 (0.49) | ALDH1A1DHODHHSD17B10MCL1 | |
| SCHEMBL7575249 | 0.81 | ALDH1A1 (0.49) | ALDH1A1DHODHTP53CYP1A2HIF1A | |
| SCHEMBL7024435 | 0.78 | AOX1 (0.74) | ALDH1A1HSD17B10 | |
| SCHEMBL7566734 | 0.77 | KDM4E (0.51) | ALDH1A1PARP1HSD17B10 | |
| SCHEMBL7030651 | 0.77 | MEN1 (0.53) | ALDH1A1PARP1TP53CYP1A2 | |
| SCHEMBL7572783 | 0.77 | ALDH1A1 (0.45) | ALDH1A1DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1116285-C | Bis(acridinecarboxamide) and Bis(phenazinecarboxamide) as antitumour agents | XENOVA LTD (GB) | 2003-07-30 | — | — | CN | disclosed |
| EP-0934278-B1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LTD (GB) | 2002-09-04 | — | — | EP | disclosed |
| US-6114332-A | BACTERICIDES | XENOVA LIMITED (GB) | 2000-09-05 | — | — | US | disclosed |
| CN-1240430-A | Bis(acridinecarboxamide) and Bis(phenazinecarboxamide) as antitumour agents | XENOVA LTD (GB) | 2000-01-05 | — | — | CN | disclosed |
| EP-0934278-A1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LIMITED (GB) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998017650-A1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LIMITED (GB) | 1998-04-30 | — | — | WO | disclosed |