SCHEMBL756808

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL755081	0.82	PLG (0.49)	ARALDH1A1KDM4EHPGDCYP3A4
	SCHEMBL752231	0.79	AR (0.56)	ARALDH1A1KDM4EHPGDCYP3A4
	SCHEMBL757274	0.78	BCHE (0.50)	ARALDH1A1KDM4EHPGDCYP3A4
	SCHEMBL753327	0.78	AR (0.47)	ARALDH1A1KDM4EHPGDCYP3A4
	SCHEMBL752352	0.72	AR (0.40)	ARALDH1A1KDM4EHPGDCYP3A4
	SCHEMBL4929225	0.71	ALDH1A1 (0.43)	ARALDH1A1KDM4EHPGDCYP3A4
	SCHEMBL16921594	0.71	BRD4 (0.58)	ARALDH1A1KDM4EHPGDCYP3A4
	SCHEMBL16908927	0.70	BRD4 (0.47)	POLHBCHEACHEPLGELANE
	SCHEMBL752863	0.69	BRD4 (0.44)	KDM4EMAPTLMNABCHEACHE
	SCHEMBL17847645	0.66	ALDH1A1 (0.38)	ALDH1A1KDM4EHPGDHSD17B10MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.