SCHEMBL752231

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL756808	0.79	AR (0.42)	ARATMCYP3A4MAPTMEN1
	SCHEMBL752352	0.76	AR (0.40)	ARATMCYP3A4MAPTALDH1A1
	SCHEMBL757274	0.76	BCHE (0.50)	ARCYP3A4MAPTMEN1KMT2A
	SCHEMBL753327	0.75	AR (0.47)	ARCYP3A4MAPTMEN1KMT2A
	SCHEMBL12636899	0.72	AR (1.00)	ARATMCYP3A4MAPTMEN1
	SCHEMBL6094870	0.71	CYP3A4 (0.85)	ARATMCYP3A4MAPTMEN1
	SCHEMBL620145	0.71	MAPT (0.64)	ARATMCYP3A4MAPTMEN1
	SCHEMBL31670262	0.71	MAPT (0.64)	ARATMCYP3A4MAPTMEN1
	SCHEMBL14145325	0.70	CYP3A4 (0.76)	ARATMCYP3A4MAPTMEN1
	SCHEMBL311843	0.70	CYP3A4 (0.59)	ARATMCYP3A4MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.