Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CDC25B | P30305 | 3/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | LDHA | P00338 | 1/20 | 0.45 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29946509 | 0.86 | GFER (0.56) | KDM4EMEN1HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL9290336 | 0.82 | NPC1 (0.54) | KDM4EMEN1HPGDKMT2ALMNA | |
| Salicylic Acid SCHEMBL17712461 | 0.75 | ALDH1A1 (0.60) | KDM4EMEN1HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL4593816 | 0.74 | CDC25B (0.61) | KDM4EMEN1HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL4268 | 0.74 | ALDH1A1 (0.61) | KDM4EMEN1HPGDKMT2AALDH1A1 | |
| SCHEMBL29376732 | 0.74 | ALDH1A1 (0.61) | KDM4EMEN1HPGDKMT2AALDH1A1 | |
| SCHEMBL29593799 | 0.74 | ALDH1A1 (0.61) | KDM4EMEN1HPGDKMT2AALDH1A1 | |
| SCHEMBL13936398 | 0.74 | DHODH (0.64) | KDM4EMEN1KMT2ALMNAALDH1A1 | |
| Phenol SCHEMBL27740227 | 0.73 | ABCG2 (0.55) | KDM4EMEN1HPGDKMT2AALDH1A1 | |
| SCHEMBL4959080 | 0.72 | ALDH1A1 (0.59) | KDM4EMEN1HPGDKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020035137-A1 | Amino (oxo) acetic acid protein tyrosine phosphatase inhibitors | ABBOTT LABORATORIES | 2002-03-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020035137-A1 | Amino (oxo) acetic acid protein tyrosine phosphatase inhibitors | PPM1A, PTPRO, PTP4A1 | KDM4E 2015/4885MEN1 3065/4885HPGD 2547/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.