Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.52 |
| ▸ | CDC25B | P30305 | 3/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | SRC | P12931 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7568133 | 0.86 | KDM4E (0.50) | GFERALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL22750628 | 0.85 | KDM4E (0.57) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL22758443 | 0.82 | ALDH1A1 (0.51) | GFERALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL11777297 | 0.81 | MEN1 (0.55) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL9281809 | 0.80 | GFER (0.76) | GFERALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL4971446 | 0.80 | ALOX15 (0.67) | KDM4EMEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL24953153 | 0.77 | ALOX15 (0.56) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL29625679 | 0.77 | ALOX15 (0.56) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| Salicylic Acid SCHEMBL17712461 | 0.77 | ALDH1A1 (0.60) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL4593816 | 0.77 | CDC25B (0.61) | GFERKDM4EMEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220304958-A1 | SMALL MOLECULE INHIBITORS OF A PROTEIN COMPLEX | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2022-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220304958-A1 | SMALL MOLECULE INHIBITORS OF A PROTEIN COMPLEX | SERBP1, PPHLN1, VCAM1 | GFER 4298/4885ALDH1A1 4523/4885KDM4E 1046/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.