Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NPY1R | P25929 | 1/20 | 0.41 |
| ▸ | NPY2R | P49146 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7573969 | 0.89 | PPARA (0.43) | PPARAKDM4EHTTLMNAMEN1 | |
| SCHEMBL7564788 | 0.87 | KDM4E (0.47) | KDM4EHTTLMNAMAPTMEN1 | |
| SCHEMBL5459806 | 0.81 | ALDH1A1 (0.50) | KDM4EHTTLMNAKMT2AHSD17B10 | |
| SCHEMBL8413334 | 0.79 | RAD52 (0.54) | RAD52KDM4EKMT2ANPC1GAA | |
| SCHEMBL7564771 | 0.78 | RAD52 (0.59) | RAD52PPARAKDM4EHTTLMNA | |
| SCHEMBL2312441 | 0.78 | MAPT (0.51) | KDM4EHTTMAPTMEN1KMT2A | |
| SCHEMBL7567419 | 0.77 | RAD52 (0.60) | RAD52HTTMAPTRXFP1 | |
| SCHEMBL7568079 | 0.77 | ALDH1A1 (0.51) | KDM4EHTTLMNAMAPTMEN1 | |
| SCHEMBL7568141 | 0.76 | RAD52 (0.52) | RAD52KDM4EHTTMAPTKMT2A | |
| SCHEMBL31125288 | 0.76 | KDM4E (0.48) | KDM4EHTTLMNAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1116285-C | Bis(acridinecarboxamide) and Bis(phenazinecarboxamide) as antitumour agents | XENOVA LTD (GB) | 2003-07-30 | — | — | CN | disclosed |
| EP-0934278-B1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LTD (GB) | 2002-09-04 | — | — | EP | disclosed |
| US-6114332-A | BACTERICIDES | XENOVA LIMITED (GB) | 2000-09-05 | — | — | US | disclosed |
| CN-1240430-A | Bis(acridinecarboxamide) and Bis(phenazinecarboxamide) as antitumour agents | XENOVA LTD (GB) | 2000-01-05 | — | — | CN | disclosed |
| EP-0934278-A1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LIMITED (GB) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998017650-A1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LIMITED (GB) | 1998-04-30 | — | — | WO | disclosed |