Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL927722 | 0.76 | HPGD (0.39) | KDM4EALDH1A1LMNAHPGDTSHR | |
| SCHEMBL928694 | 0.72 | HTT (0.40) | KDM4EALDH1A1LMNAHPGDTSHR | |
| SCHEMBL13668155 | 0.69 | HSD17B10 (0.42) | KDM4EALDH1A1LMNAHPGDTSHR | |
| SCHEMBL12116704 | 0.68 | KDM4E (0.61) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL229426 | 0.68 | TP53 (0.68) | KDM4EALDH1A1SMN1; SMN2HTTTP53 | |
| SCHEMBL6142493 | 0.66 | TP53 (0.65) | KDM4EALDH1A1SMN1; SMN2HTTTP53 | |
| SCHEMBL5692672 | 0.63 | PDPK1 (0.64) | ALDH1A1TSHRHSD17B10RAB9A | |
| SCHEMBL29979980 | 0.63 | HTT (0.43) | KDM4EALDH1A1LMNAHPGDTSHR | |
| SCHEMBL1020149 | 0.63 | HTT (0.43) | KDM4EALDH1A1LMNAHPGDTSHR | |
| SCHEMBL231419 | 0.63 | KDM4E (0.64) | KDM4EALDH1A1LMNAHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020176843-A1 | Polyamide particles as anti-irritant agents | L'OREAL (FR) | 2002-11-28 | — | — | US | disclosed |