Sugi Predict

Sugi Predict / Compounds / SCHEMBL928694

SCHEMBL928694

SCHEMBL928694

C[Si](C)(C)O[Si](C)(CCCn1c(-c2nc3ccccc3o2)nc2ccccc21)O[Si](C)(C)C

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ HTT P42858 2/20 0.40
▸ HPGD P15428 2/20 0.40
▸ TP53 P04637 3/20 0.40
▸ LMNA P02545 3/20 0.39
▸ TRPV4 Q9HBA0 1/20 0.39
▸ GAA P10253 2/20 0.39
▸ SMN1; SMN2 Q16637 2/20 0.39
▸ KDM4E B2RXH2 5/20 0.39
▸ ALDH1A1 P00352 3/20 0.38
▸ NPSR1 Q6W5P4 2/20 0.38
▸ HSD17B10 Q99714 1/20 0.38
▸ TSHR P16473 1/20 0.38
▸ DRD2 P14416 1/20 0.38
▸ DRD3 P35462 1/20 0.38
▸ NPC1 O15118 1/20 0.37
▸ RAB9A P51151 1/20 0.37
▸ CXCR4 P61073 1/20 0.37
▸ TLR8 Q9NR97 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL927859 0.87 HTT (0.44) HTTHPGDTP53LMNATRPV4
SCHEMBL13620681 0.78 ALDH1A1 (0.56) HTTHPGDTP53LMNAGAA
SCHEMBL927722 0.76 HPGD (0.39) HTTHPGDTP53LMNAGAA
SCHEMBL10061924 0.73 ALDH1A1 (0.56) HTTHPGDTP53LMNAGAA
SCHEMBL7568149 0.72 KDM4E (0.39) HTTHPGDTP53LMNAGAA
SCHEMBL7037504 0.72 KDM4E (0.58) HTTHPGDTP53LMNAGAA
SCHEMBL10061948 0.72 TP53 (0.45) HPGDTP53LMNAGAASMN1; SMN2
SCHEMBL8094851 0.70 KDM4E (0.47) HTTHPGDTP53LMNAGAA
SCHEMBL12387035 0.67 ALDH1A1 (0.52) HPGDTP53LMNAGAASMN1; SMN2
SCHEMBL10005374 0.66 TLR8 (0.71) HTTHPGDTP53LMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1028120-B1 Organosilicon compounds with N-substituted benzimidazole-benzazole or benzofuranyl-benzazole groups, sunscreen compositions containing these compounds and their use OREAL (FR) 2003-03-19 — — EP claimed
US-6221343-B1 Benzimidazole/benzofuryl-benzazole silicon compounds and UV-photoprotective compositions comprised thereof SOCIETE L'OREAL S.A. (FR) 2001-04-24 — — US claimed
EP-1028120-A1 Organosilicon compounds with N-substituted benzimidazole-benzazole or benzofuranyl-benzazole groups, sunscreen compositions containing these compounds and their use L'OREAL (FR) 2000-08-16 — — EP claimed
US-20230149289-A1 COSMETIC COMPOSITION FOR FORMING A FILM HAVING ELEVATED ELASTICITY AND EXTENSIBILITY COVESTRO DEUTSCHLAND AG (DE) 2023-05-18 — — US disclosed
CN-115209863-A Cosmetic composition for forming film with improved elasticity and extensibility 科思创德国股份有限公司 2022-10-18 — — CN disclosed
EP-3888627-A1 BIO-BASED POLYURETHANE DISPERSIONS FOR DECORATIVE COSMETIC APPLICATIONS Covestro Deutschland AG (DE) 2021-10-06 — — EP disclosed
EP-3889196-A1 BIOBASED POLYURETHANE DISPERSIONS FOR SUNSCREEN APPLICATIONS Covestro Deutschland AG (DE) 2021-10-06 — — EP disclosed
US-20210186849-A1 POLYURETHANE UREA SOLUTIONS FOR COSMETIC COMPOSITIONS COVESTRO DEUTSCHLAND AG (DE) 2021-06-24 — — US disclosed
EP-2271305-B1 SUNSCREEN COMPOSITIONS COVESTRO DEUTSCHLAND AG (DE) 2019-09-04 — — EP disclosed
EP-2271306-B1 DECORATIVE COSMETIC COMPOUNDS COVESTRO DEUTSCHLAND AG (DE) 2019-08-28 — — EP disclosed
US-20190110977-A1 PROCESS FOR TREATMENT OF KERATINOUS MATERIALS AND KIT FOR FORMULATION OF A COSMETIC PRODUCT L'OREAL (FR) 2019-04-18 — — US disclosed
EP-1249227-A1 Antiwrinkle composition with immediate effect based on an aqueous dispersion of at least one mineral filler L'OREAL (FR) 2002-10-16 — — EP disclosed
EP-1245222-A2 Topical composition containing fibres and enzymes L'OREAL (FR) 2002-10-02 — — EP disclosed
EP-1243252-A1 Skin composition containing fibres and ubiquinones L'OREAL (FR) 2002-09-25 — — EP disclosed
EP-1243253-A1 Composition containing fibres and steroids L'OREAL (FR) 2002-09-25 — — EP disclosed
EP-1243254-A1 Composition containing fibres and a flavonoid L'OREAL (FR) 2002-09-25 — — EP disclosed
EP-1234570-A1 Cosmetic use of a matifying composition for treating greasy skin L'OREAL (FR) 2002-08-28 — — EP disclosed
WO-2002055046-A1 COSMETIC COMPOSITION CONTAINING MINERAL FILTERS L'OREAL (FR) 2002-07-18 — — WO disclosed
US-6221343-B1 Benzimidazole/benzofuryl-benzazole silicon compounds and UV-photoprotective compositions comprised thereof SOCIETE L'OREAL S.A. (FR) 2001-04-24 — — US disclosed
EP-1028120-A1 Organosilicon compounds with N-substituted benzimidazole-benzazole or benzofuranyl-benzazole groups, sunscreen compositions containing these compounds and their use L'OREAL (FR) 2000-08-16 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230149289-A1 COSMETIC COMPOSITION FOR FORMING A FILM HAVING ELEVATED ELASTICITY AND EXTENSIBILITY POLR1C, CUTA, SUCLG1 HTT 382/4885HPGD 1069/4885TP53 3075/4885
US-20190110977-A1 PROCESS FOR TREATMENT OF KERATINOUS MATERIALS AND KIT FOR FORMULATION OF A COSMETIC PRODUCT CUTA, KRT18, KIT HTT 2336/4885HPGD 3100/4885TP53 471/4885
US-20210186849-A1 POLYURETHANE UREA SOLUTIONS FOR COSMETIC COMPOSITIONS KRT18, POLR1C, CUTA HTT 205/4885HPGD 1050/4885TP53 238/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.