SCHEMBL927722

SCHEMBL927722

C[Si](C)(C)O[Si](C)(CCCn1c(-c2nc3ccccc3s2)nc2ccccc21)O[Si](C)(C)C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 4/20 0.39
HTT P42858 3/20 0.39
LMNA P02545 6/20 0.39
TSHR P16473 5/20 0.39
NPC1 O15118 3/20 0.39
RAB9A P51151 3/20 0.39
TP53 P04637 4/20 0.39
SMN1; SMN2 Q16637 5/20 0.38
GAA P10253 2/20 0.38
KDM4E B2RXH2 7/20 0.38
ALDH1A1 P00352 5/20 0.38
HSD17B10 Q99714 3/20 0.38
MAPT P10636 2/20 0.38
MAPK1 P28482 2/20 0.38
CASP1 P29466 1/20 0.38
NPSR1 Q6W5P4 3/20 0.37
DRD2 P14416 2/20 0.37
DRD3 P35462 1/20 0.37
DRD4 P21917 1/20 0.37
GRM2 Q14416 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29979980 0.87 HTT (0.43) HPGDHTTLMNATSHRNPC1
SCHEMBL1020149 0.87 HTT (0.43) HPGDHTTLMNATSHRNPC1
SCHEMBL14582034 0.82 TLR8 (0.55) HPGDHTTLMNATSHRNPC1
SCHEMBL7038401 0.81 LMNA (0.42) HPGDHTTLMNATSHRNPC1
SCHEMBL928694 0.76 HTT (0.40) HPGDHTTLMNATSHRNPC1
SCHEMBL7568149 0.76 KDM4E (0.39) HPGDHTTLMNATSHRRAB9A
SCHEMBL7040964 0.72 HSD17B10 (0.64) HPGDHTTLMNATSHRNPC1
SCHEMBL7035923 0.71 KDM4E (0.59) HPGDHTTLMNATSHRNPC1
SCHEMBL8104229 0.69 ALDH1A1 (0.42) HPGDHTTLMNATSHRNPC1
SCHEMBL9331260 0.65 MAPK1 (0.53) HTTLMNATSHRNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1028120-B1 Organosilicon compounds with N-substituted benzimidazole-benzazole or benzofuranyl-benzazole groups, sunscreen compositions containing these compounds and their use OREAL (FR) 2003-03-19 EP claimed
US-6221343-B1 Benzimidazole/benzofuryl-benzazole silicon compounds and UV-photoprotective compositions comprised thereof SOCIETE L'OREAL S.A. (FR) 2001-04-24 US claimed
EP-1028120-A1 Organosilicon compounds with N-substituted benzimidazole-benzazole or benzofuranyl-benzazole groups, sunscreen compositions containing these compounds and their use L'OREAL (FR) 2000-08-16 EP claimed
US-20230149289-A1 COSMETIC COMPOSITION FOR FORMING A FILM HAVING ELEVATED ELASTICITY AND EXTENSIBILITY COVESTRO DEUTSCHLAND AG (DE) 2023-05-18 US disclosed
US-20230135505-A1 BIO-BASED POLYURETHANE DISPERSIONS FOR DECORATIVE COSMETIC APPLICATIONS COVESTRO DEUTSCHLAND AG (DE) 2023-05-04 US disclosed
EP-4114347-A1 COSMETIC COMPOSITION FOR FORMING A FILM HAVING ELEVATED ELASTICITY AND EXTENSIBILITY Covestro Deutschland AG (DE) 2023-01-11 EP disclosed
CN-115209863-A Cosmetic composition for forming film with improved elasticity and extensibility 科思创德国股份有限公司 2022-10-18 CN disclosed
EP-3177267-B1 POLYURETHANEUREA SOLUTIONS FOR COSMETIC COMPOSITIONS COVESTRO DEUTSCHLAND AG (DE) 2022-01-05 EP disclosed
EP-3888627-A1 BIO-BASED POLYURETHANE DISPERSIONS FOR DECORATIVE COSMETIC APPLICATIONS Covestro Deutschland AG (DE) 2021-10-06 EP disclosed
EP-3889196-A1 BIOBASED POLYURETHANE DISPERSIONS FOR SUNSCREEN APPLICATIONS Covestro Deutschland AG (DE) 2021-10-06 EP disclosed
US-20210186849-A1 POLYURETHANE UREA SOLUTIONS FOR COSMETIC COMPOSITIONS COVESTRO DEUTSCHLAND AG (DE) 2021-06-24 US disclosed
EP-1262168-A1 Composition containing fibres to combat the skin aging process L'OREAL (FR) 2002-12-04 EP disclosed
US-20020176843-A1 Polyamide particles as anti-irritant agents L'OREAL (FR) 2002-11-28 US disclosed
US-20020172647-A1 Composition containing a steroid and a liposoluble UV filter L'OREAL (FR) 2002-11-21 US disclosed
EP-1249227-A1 Antiwrinkle composition with immediate effect based on an aqueous dispersion of at least one mineral filler L'OREAL (FR) 2002-10-16 EP disclosed
EP-1245222-A2 Topical composition containing fibres and enzymes L'OREAL (FR) 2002-10-02 EP disclosed
EP-1243253-A1 Composition containing fibres and steroids L'OREAL (FR) 2002-09-25 EP disclosed
EP-1243252-A1 Skin composition containing fibres and ubiquinones L'OREAL (FR) 2002-09-25 EP disclosed
EP-1243254-A1 Composition containing fibres and a flavonoid L'OREAL (FR) 2002-09-25 EP disclosed
EP-1234570-A1 Cosmetic use of a matifying composition for treating greasy skin L'OREAL (FR) 2002-08-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230149289-A1 COSMETIC COMPOSITION FOR FORMING A FILM HAVING ELEVATED ELASTICITY AND EXTENSIBILITY POLR1C, CUTA, SUCLG1 HPGD 1069/4885HTT 382/4885LMNA 1070/4885
US-20020172647-A1 Composition containing a steroid and a liposoluble UV filter SHBG, GLA, LIPA HPGD 895/4885HTT 2248/4885LMNA 272/4885
US-20210186849-A1 POLYURETHANE UREA SOLUTIONS FOR COSMETIC COMPOSITIONS KRT18, POLR1C, CUTA HPGD 1050/4885HTT 205/4885LMNA 985/4885
US-20230135505-A1 BIO-BASED POLYURETHANE DISPERSIONS FOR DECORATIVE COSMETIC APPLICATIONS UROD, PUF60, DDT HPGD 111/4885HTT 1380/4885LMNA 2061/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.