Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 6/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.50 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.46 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | CETP | P11597 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7569415 | 0.84 | KDM4E (0.60) | HDAC3HDAC1ERAP2LNPEPPOLB | |
| SCHEMBL7572903 | 0.81 | MAPT (0.56) | MAPT | |
| SCHEMBL5591927 | 0.79 | PRKCI (0.61) | TSHRALDH1A1GAAHSP90AA1HSP90AB1 | |
| SCHEMBL8396604 | 0.78 | GAA (0.56) | HDAC3HDAC1POLBNCOR2HDAC2 | |
| SCHEMBL27757715 | 0.77 | HDAC1 (0.62) | HDAC3HDAC1POLBNCOR2HDAC2 | |
| SCHEMBL2952990 | 0.74 | HSP90AA1 (0.57) | TSHRALDH1A1HSP90AA1HSP90AB1HPGD | |
| SCHEMBL31621299 | 0.74 | HSP90AA1 (0.57) | TSHRALDH1A1HSP90AA1HSP90AB1HPGD | |
| SCHEMBL27736940 | 0.73 | HDAC3 (0.78) | HDAC3HDAC1POLBNCOR2TSHR | |
| SCHEMBL2618087 | 0.73 | HDAC1 (0.64) | HDAC3HDAC1NCOR2HDAC2HDAC4 | |
| SCHEMBL27736941 | 0.73 | KDM4E (0.59) | HDAC3HDAC1POLBNCOR2HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0685470-B1 | Benzene derivatives and pharmaceutical composition | KUREHA CHEMICAL IND CO LTD (JP) | 2002-09-11 | — | — | EP | disclosed |
| EP-0685470-A2 | Benzene derivatives and pharmaceutical composition | Kureha Chemical Industry Co., Ltd. (JP) | 1995-12-06 | — | — | EP | disclosed |