Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | PDCD1 | Q15116 | 3/20 | 0.53 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KDM4A | O75164 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29534084 | 1.00 | ALDH1A1 (0.54) | ALDH1A1PDCD1CD274KMT2AMEN1 | |
| SCHEMBL756835 | 1.00 | ALDH1A1 (0.54) | ALDH1A1PDCD1CD274KMT2AMEN1 | |
| SCHEMBL750948 | 0.89 | ALDH1A1 (0.54) | ALDH1A1KMT2AMEN1KDM4ETSHR | |
| SCHEMBL4962448 | 0.89 | ALDH1A1 (0.54) | ALDH1A1KMT2AMEN1KDM4ETSHR | |
| SCHEMBL750949 | 0.89 | ALDH1A1 (0.54) | ALDH1A1KMT2AMEN1KDM4ETSHR | |
| SCHEMBL30025474 | 0.89 | ALDH1A1 (0.54) | ALDH1A1KMT2AMEN1KDM4ETSHR | |
| SCHEMBL5842171 | 0.87 | ALDH1A1 (0.53) | ALDH1A1KMT2AMEN1KDM4ETSHR | |
| SCHEMBL5842162 | 0.87 | ALDH1A1 (0.53) | ALDH1A1KMT2AMEN1KDM4ETSHR | |
| SCHEMBL14921097 | 0.86 | ALDH1A1 (0.66) | ALDH1A1KMT2AMEN1KDM4EL3MBTL1 | |
| SCHEMBL10013396 | 0.85 | MEN1 (0.49) | ALDH1A1PDCD1CD274KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9624485-B2 | Genetic incorporation of unnatural amino acids into proteins in mammalian cells | THE SCRIPPS RESEARCH INSTITUTE (US) | 2017-04-18 | — | — | US | claimed |
| US-20100021963-A1 | Genetic incorporation of unnatural amino acids into proteins in mammalian cells | THE SCRIPPS RESEARCH INSTITUTE | 2010-01-28 | — | — | US | claimed |
| EP-2069481-A2 | GENETIC INCORPORATION OF UNNATURAL AMINO ACIDS INTO PROTEINS IN MAMMALIAN CELLS | The Scripps Research Institute (US) | 2009-06-17 | — | — | EP | claimed |
| US-20080233611-A1 | Orthogonal Translation Components for the in Vivo Incorporation of Unnatural Amino Acids | THE SCRIPPS RESEARCH INSTITUTE (US) | 2008-09-25 | — | — | US | claimed |
| US-20080166766-A1 | Genetic incorporation of unnatural amino acids into proteins in mammalian cells | THE SCRIPPS RESEARCH INSTITUTE (US) | 2008-07-10 | — | — | US | claimed |
| WO-2008073184-A2 | GENETIC INCORPORATION OF UNNATURAL AMINO ACIDS INTO PROTEINS IN MAMMALIAN CELLS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2008-06-19 | — | — | WO | claimed |
| EP-1807515-A4 | ORTHOGONAL TRANSLATION COMPONENTS FOR THE IN VIVO INCORPORATION OF UNNATURAL AMINO ACIDS | SCRIPPS RESEARCH INST (US) | 2008-06-18 | — | — | EP | claimed |
| EP-1807515-A2 | ORTHOGONAL TRANSLATION COMPONENTS FOR THE IN VIVO INCORPORATION OF UNNATURAL AMINO ACIDS | The Scripps Research Institute (US) | 2007-07-18 | — | — | EP | claimed |
| WO-2006110182-A2 | ORTHOGONAL TRANSLATION COMPONENTS FOR THE IN VIVO INCORPORATION OF UNNATURAL AMINO ACIDS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2006-10-19 | — | — | WO | claimed |
| EP-4720264-A1 | AMINOACYL-TRNA SYNTHETASE SETS | United Kingdom Research and Innovation (GB) | 2026-04-08 | — | — | EP | disclosed |
| US-20250346939-A1 | Method of Making Proteins with Non-Standard Amino Acids | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2025-11-13 | — | — | US | disclosed |
| US-20250320452-A1 | MICROORGANISMS AND USES THEREOF | RES & INNOVATION UK (GB) | 2025-10-16 | — | — | US | disclosed |
| US-20250279156-A1 | METHODS FOR OPTIMISING PROTEIN PRODUCTION | UNITED KINGDOM RESEARCH AND INNOVATION (GB) | 2025-09-04 | — | — | US | disclosed |
| US-12385035-B2 | Synthetic genome | UNITED KINGDOM RESEARCH AND INNOVATION (GB) | 2025-08-12 | — | — | US | disclosed |
| EP-0602899-B1 | Modified proteins containing controllable intervening sequences and methods of their production | NEW ENGLAND BIOLABS INC (US) | 2004-10-20 | — | — | EP | disclosed |
| EP-0835323-A4 | MODIFIED PROTEINS AND METHODS OF THEIR PRODUCTION | NEW ENGLAND BIOLABS INC (US) | 1999-08-11 | — | — | EP | disclosed |
| US-5834247-A | Modified proteins comprising controllable intervening protein sequences or their elements methods of producing same and methods for purification of a target protein comprised by a modified protein | NEW ENGLAND BIOLABS, INC. (US) | 1998-11-10 | — | — | US | disclosed |
| EP-0835323-A1 | MODIFIED PROTEINS AND METHODS OF THEIR PRODUCTION | NEW ENGLAND BIOLABS, INC. (US) | 1998-04-15 | — | — | EP | disclosed |
| WO-1997001642-A1 | MODIFIED PROTEINS AND METHODS OF THEIR PRODUCTION | NEW ENGLAND BIOLABS, INC. (US) | 1997-01-16 | — | — | WO | disclosed |
| EP-0602899-A2 | Modified proteins containing controllable intervening sequences and methods of their production | NEW ENGLAND BIOLABS, INC. (US) | 1994-06-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080233611-A1 | Orthogonal Translation Components for the in Vivo Incorporation of Unnatural Amino Acids | AARS1, NSUN3, OSGEP | ALDH1A1 4157/4885PDCD1 3832/4885CD274 4548/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.