Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.40 |
| ▸ | CDC7 | O00311 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30908843 | 0.82 | HTR6 (0.44) | — | |
| SCHEMBL30908850 | 0.79 | HTR6 (0.41) | — | |
| Hydrochloric Acid SCHEMBL30909074 | 0.78 | HTR6 (0.40) | — | |
| SCHEMBL30908984 | 0.74 | HTR6 (0.40) | MAPTCDK2KDM2B | |
| SCHEMBL7570882 | 0.71 | OPRM1 (0.39) | MAPTCYP19A1KDM2B | |
| SCHEMBL7569682 | 0.63 | HRH3 (0.40) | CDC7CDK2KDM2B | |
| SCHEMBL6741126 | 0.62 | CYP19A1 (0.74) | MAPTCYP19A1CDC7CDK2 | |
| SCHEMBL2063978 | 0.62 | HTR2A (0.37) | CDK2 | |
| SCHEMBL30775500 | 0.60 | MAPT (0.63) | MAPTCYP19A1CDC7CDK2 | |
| SCHEMBL1150379 | 0.60 | CYP19A1 (0.70) | MAPTCYP19A1CDC7CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1204662-A1 | AZAINDOLES HAVING SEROTONIN RECEPTOR AFFINITY | NPS Allelix Corp. (CA) | 2002-05-15 | — | — | EP | claimed |
| WO-2001012629-A1 | AZAINDOLES HAVING SEROTONIN RECEPTOR AFFINITY | NPS ALLELIX CORP. (US) | 2001-02-22 | — | — | WO | claimed |
| EP-1204662-A1 | AZAINDOLES HAVING SEROTONIN RECEPTOR AFFINITY | NPS Allelix Corp. (CA) | 2002-05-15 | — | — | EP | disclosed |
| WO-2001012629-A1 | AZAINDOLES HAVING SEROTONIN RECEPTOR AFFINITY | NPS ALLELIX CORP. (US) | 2001-02-22 | — | — | WO | disclosed |