Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | FNTA | P49354 | 1/20 | 0.43 |
| ▸ | FNTB | P49356 | 1/20 | 0.43 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7572481 | 0.86 | HTT (0.54) | KDM4EALDH1A1MAPK1HPGDTSHR | |
| SCHEMBL7576242 | 0.80 | AR (0.44) | FNTAFNTBPGGT1BTSHRAR | |
| SCHEMBL7571033 | 0.80 | AR (0.44) | FNTAFNTBPGGT1BTSHRAR | |
| SCHEMBL7570106 | 0.79 | SIGMAR1 (0.42) | FNTAFNTBPGGT1BAR | |
| SCHEMBL7570115 | 0.75 | RAB9A (0.52) | ALDH1A1MAPK1HPGDHSD17B10 | |
| SCHEMBL7572477 | 0.74 | FNTA (0.48) | MAPK1FNTAFNTBPGGT1B | |
| SCHEMBL7570578 | 0.73 | FNTA (0.42) | MAPK1FNTAFNTBPGGT1B | |
| SCHEMBL18406703 | 0.72 | FNTA (0.50) | FNTAFNTBPGGT1BTSHRAR | |
| SCHEMBL6982380 | 0.72 | NR1D1 (0.44) | FNTAFNTBPGGT1B | |
| Hydrochloric Acid SCHEMBL7567497 | 0.71 | NR1D1 (0.44) | FNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020019527-A1 | Substituted phenyl farnesyltransferase inhibitors | ABBOTT LABORATORIES | 2002-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020019527-A1 | Substituted phenyl farnesyltransferase inhibitors | FNTA, FNTB, SLC10A1 | KDM4E 3715/4885ALDH1A1 385/4885GAA 253/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.