Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 19/20 | 0.47 |
| ▸ | GABRD | O14764 | 19/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 19/20 | 0.47 |
| ▸ | GABRB1 | P18505 | 19/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 19/20 | 0.47 |
| ▸ | GABRB3 | P28472 | 19/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 19/20 | 0.47 |
| ▸ | GABRA3 | P34903 | 19/20 | 0.47 |
| ▸ | GABRA2 | P47869 | 19/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 19/20 | 0.47 |
| ▸ | GABRA4 | P48169 | 19/20 | 0.47 |
| ▸ | GABRE | P78334 | 19/20 | 0.47 |
| ▸ | GABRA6 | Q16445 | 19/20 | 0.47 |
| ▸ | GABRG1 | Q8N1C3 | 19/20 | 0.47 |
| ▸ | GABRG3 | Q99928 | 19/20 | 0.47 |
| ▸ | GABRQ | Q9UN88 | 19/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6055819 | 0.85 | GABRP (0.52) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8527201 | 0.82 | GABRP (0.49) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7575328 | 0.80 | GABRP (0.57) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7711423 | 0.76 | GABRP (0.52) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7707158 | 0.76 | GABRA2 (0.57) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL25897 | 0.75 | GABRP (0.51) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL5203592 | 0.75 | GABRP (0.61) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL20089290 | 0.74 | GABRP (0.53) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7580327 | 0.74 | GABRP (0.66) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL3826379 | 0.74 | GABRP (0.49) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5907041-A | FROM A DIAZONIUM SALT | RHONE-POULENC INC. (US) | 1999-05-25 | — | — | US | claimed |
| EP-0966444-B1 | PROCESS FOR PREPARING PYRAZOLE DERIVATIVES | AVENTIS CROPSCIENCE SA (FR) | 2002-09-04 | — | — | EP | disclosed |
| US-6090927-A | CYANOBUTANONE AND SUCCINONITRILE SUBSTITUTED WITH AP-CHLOROPHENYLSULFONYL- AND A 4-(TRIFLUOROMETHYL)-2,6-DICHLOROPHENYLAZO GROUP | RHONE-POULENC INC. (US) | 2000-07-18 | — | — | US | disclosed |
| EP-0966444-A1 | PROCESS FOR PREPARING PYRAZOLE DERIVATIVES | Rhone Poulenc Agro (FR) | 1999-12-29 | — | — | EP | disclosed |
| US-5907041-A | FROM A DIAZONIUM SALT | RHONE-POULENC INC. (US) | 1999-05-25 | — | — | US | disclosed |
| WO-1998040358-A1 | PROCESS FOR PREPARING PYRAZOLE DERIVATIVES | RHONE-POULENC AGRO (FR) | 1998-09-17 | — | — | WO | disclosed |