Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.49 |
| ▸ | NPC1 | O15118 | 8/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 6/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7549362 | 0.75 | ALDH1A1 (0.57) | RAB9ANPC1CASP1SMN1; SMN2CYP1A2 | |
| SCHEMBL1827277 | 0.68 | RAB9A (0.50) | RAB9ANPC1CASP1SMN1; SMN2CYP1A2 | |
| SCHEMBL27553475 | 0.67 | RAB9A (0.52) | RAB9ANPC1CASP1SMN1; SMN2CYP1A2 | |
| SCHEMBL11564363 | 0.65 | TSHR (0.55) | SMN1; SMN2CYP1A2CYP2C19ALDH1A1TSHR | |
| SCHEMBL13387564 | 0.65 | GAA (0.59) | SMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL4719490 | 0.65 | GAA (0.59) | SMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL7564852 | 0.65 | RAB9A (0.79) | RAB9ANPC1CASP1SMN1; SMN2CYP1A2 | |
| SCHEMBL994563 | 0.65 | RAB9A (0.55) | RAB9ANPC1CASP1SMN1; SMN2CYP1A2 | |
| SCHEMBL2903601 | 0.64 | RAB9A (0.51) | RAB9ANPC1CASP1SMN1; SMN2CYP1A2 | |
| SCHEMBL2906397 | 0.64 | RAB9A (0.51) | RAB9ANPC1CASP1SMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1210324-A1 | SUBSTITUTED CYCLOPENTENES, THEIR PREPARATION AND THEIR USE FOR CHIRAL SCAFFOLDS | Chirotech Technology Limited (GB) | 2002-06-05 | — | — | EP | disclosed |
| WO-2001017952-A1 | SUBSTITUTED CYCLOPENTENES, THEIR PREPARATION AND THEIR USE FOR CHIRAL SCAFFOLDS | CHIROTECH TECHNOLOGY LIMITED (GB) | 2001-03-15 | — | — | WO | disclosed |