Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 8/20 | 0.55 |
| ▸ | ACE | P12821 | 7/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7574571 | 0.89 | MME (0.49) | MMEACEMEN1KMT2ALPAR1 | |
| SCHEMBL7566349 | 0.86 | MME (0.57) | MMEACEMEN1KMT2A | |
| SCHEMBL7568978 | 0.82 | MME (0.78) | MMEACEMEN1KMT2A | |
| SCHEMBL8669828 | 0.80 | KMT2A (0.49) | MEN1KMT2A | |
| SCHEMBL7568214 | 0.77 | MME (0.81) | MMEACE | |
| SCHEMBL7567122 | 0.77 | MME (0.81) | MMEACE | |
| SCHEMBL7567634 | 0.77 | MME (0.49) | MMEACEMEN1KMT2A | |
| SCHEMBL7568168 | 0.77 | MME (0.60) | MMEACEMEN1KMT2A | |
| SCHEMBL7567517 | 0.74 | MME (0.77) | MMEACE | |
| SCHEMBL7568906 | 0.74 | MME (0.77) | MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798291-B1 | NOVEL 1,3-DIALKYLUREA DERIVATIVES | SANTEN PHARMACEUTICAL CO LTD (JP) | 2002-09-11 | — | — | EP | disclosed |
| US-5968980-A | ENDOPEPTIDASE 24.11 INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-10-19 | — | — | US | disclosed |
| EP-0798291-A1 | NOVEL 1,3-DIALKYLUREA DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1997-10-01 | — | — | EP | disclosed |