Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | FPR2 | P25090 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8673938 | 0.85 | MTNR1A (0.52) | KMT2AMEN1ALDH1A1MTNR1AMTNR1B | |
| SCHEMBL7735713 | 0.83 | KMT2A (0.53) | KMT2AMEN1ALDH1A1HPGDLMNA | |
| SCHEMBL7568871 | 0.80 | MME (0.55) | KMT2AMEN1 | |
| SCHEMBL8670242 | 0.79 | CYP1A1 (0.40) | KMT2AMEN1ALDH1A1LMNATSHR | |
| SCHEMBL8668930 | 0.78 | MTNR1A (0.60) | KMT2AMEN1ALDH1A1HPGDMTNR1A | |
| SCHEMBL8673871 | 0.77 | MME (0.63) | KMT2AMEN1HSD17B10ALOX15 | |
| SCHEMBL2761181 | 0.77 | MME (0.63) | KMT2AMEN1HSD17B10ALOX15 | |
| SCHEMBL3659382 | 0.77 | MME (0.63) | KMT2AMEN1HSD17B10ALOX15 | |
| SCHEMBL29372084 | 0.77 | MME (0.63) | KMT2AMEN1HSD17B10ALOX15 | |
| SCHEMBL8669796 | 0.75 | MTNR1A (0.63) | ALDH1A1MTNR1AMTNR1BALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849781-A | Tricyclic amides | ADIR ET COMPAGNIE (FR) | 1998-12-15 | — | — | US | disclosed |
| US-5712312-A | MELATONINERGIC RECEPTOR LIGANDS, TREATMENT OF SLEEP DISORDERS | ADIR ET COMPAGNIE (FR) | 1998-01-27 | — | — | US | disclosed |