SCHEMBL7569115

SCHEMBL7569115

N#Cc1ccc(C=CC(N)=O)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.60
HDAC2 Q92769 2/20 0.60
ALDH1A1 P00352 2/20 0.60
LMNA P02545 1/20 0.60
L3MBTL1 Q9Y468 1/20 0.60
P4HB P07237 5/20 0.58
HTT P42858 1/20 0.54
SNCA P37840 1/20 0.53
CA12 O43570 1/20 0.51
CA1 P00915 1/20 0.51
CA2 P00918 1/20 0.51
CA9 Q16790 1/20 0.51
FBP1 P09467 1/20 0.49
MAOB P27338 2/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
MAOA P21397 1/20 0.48
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
GPR183 P32249 1/20 0.46
GRIK1 P39086 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8149933 1.00 MAPT (0.60) MAPTHDAC2ALDH1A1LMNAL3MBTL1
SCHEMBL7329521 0.84 MAPT (0.64) MAPTHDAC2ALDH1A1LMNAL3MBTL1
SCHEMBL8497722 0.84 MAPT (0.64) MAPTHDAC2ALDH1A1LMNAL3MBTL1
SCHEMBL1450230 0.83 F3 (0.52) MAPTHDAC2ALDH1A1LMNACA12
SCHEMBL992032 0.82 ALDH1A1 (0.67) MAPTHDAC2ALDH1A1LMNAL3MBTL1
SCHEMBL992033 0.82 ALDH1A1 (0.67) MAPTHDAC2ALDH1A1LMNAL3MBTL1
SCHEMBL14737676 0.82 KMT2A (0.52) MAPTHDAC2ALDH1A1LMNAL3MBTL1
SCHEMBL8155063 0.81 P4HB (0.43) MAPTHDAC2ALDH1A1LMNAL3MBTL1
SCHEMBL8155056 0.81 P4HB (0.43) MAPTHDAC2ALDH1A1LMNAL3MBTL1
SCHEMBL1877042 0.81 MAPT (0.60) MAPTHDAC2ALDH1A1LMNAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0934256-B1 PROCESS FOR THE PRODUCTION OF CYANOCINNAMAMIDES HONEYWELL INT INC (US) 2002-08-21 EP claimed
EP-0982356-A2 Improved stabilized coatings Clariant Finance (BVI) Limited (VG) 2000-03-01 EP claimed
EP-0934256-A1 PROCESS FOR THE PRODUCTION OF CYANOCINNAMAMIDES AlliedSignal Inc. (US) 1999-08-11 EP claimed
WO-1998016501-A1 PROCESS FOR THE PRODUCTION OF CYANOCINNAMAMIDES ALLIEDSIGNAL INC. (US) 1998-04-23 WO claimed
US-5654465-A Process for the production of cyanocinnamamides ALLIEDSIGNAL INC. (US) 1997-08-05 US claimed
CN-1040366-A Butenoic acid or acrylic acid derivative EISAI CO LTD (JP) 1990-03-14 CN claimed
EP-0934256-B1 PROCESS FOR THE PRODUCTION OF CYANOCINNAMAMIDES HONEYWELL INT INC (US) 2002-08-21 EP disclosed
EP-0934256-B1 PROCESS FOR THE PRODUCTION OF CYANOCINNAMAMIDES HONEYWELL INT INC (US) 2002-08-21 EP disclosed
US-RE36625-E Linear and cyclic polymers or oligomers having a photoreactive ethene group ROLIC AG (CH) 2000-03-21 US disclosed
EP-0982356-A2 Improved stabilized coatings Clariant Finance (BVI) Limited (VG) 2000-03-01 EP disclosed
EP-0934256-A1 PROCESS FOR THE PRODUCTION OF CYANOCINNAMAMIDES AlliedSignal Inc. (US) 1999-08-11 EP disclosed
EP-0934256-A1 PROCESS FOR THE PRODUCTION OF CYANOCINNAMAMIDES AlliedSignal Inc. (US) 1999-08-11 EP disclosed
WO-1998016501-A1 PROCESS FOR THE PRODUCTION OF CYANOCINNAMAMIDES ALLIEDSIGNAL INC. (US) 1998-04-23 WO disclosed
WO-1998016501-A1 PROCESS FOR THE PRODUCTION OF CYANOCINNAMAMIDES ALLIEDSIGNAL INC. (US) 1998-04-23 WO disclosed
US-5654465-A Process for the production of cyanocinnamamides ALLIEDSIGNAL INC. (US) 1997-08-05 US disclosed
US-5654465-A Process for the production of cyanocinnamamides ALLIEDSIGNAL INC. (US) 1997-08-05 US disclosed
US-5654465-A Process for the production of cyanocinnamamides ALLIEDSIGNAL INC. (US) 1997-08-05 US disclosed
US-5539074-A LIQUID CRYSTAL POLYMERS ON SILICA FOR LIGHT SENSITIVE ELEMENTS HOFFMANN-LA ROCHE INC. (US) 1996-07-23 US disclosed
CN-1040366-A Butenoic acid or acrylic acid derivative EISAI CO LTD (JP) 1990-03-14 CN disclosed