Sugi Predict

Sugi Predict / Compounds / SCHEMBL992032

SCHEMBL992032

SCHEMBL992032

N#Cc1ccc(/C=C/C(=O)O)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 2/20 0.67
▸ MAPT P10636 2/20 0.67
▸ LMNA P02545 1/20 0.67
▸ L3MBTL1 Q9Y468 1/20 0.67
▸ FFAR1 O14842 2/20 0.65
▸ HDAC2 Q92769 3/20 0.62
▸ P4HB P07237 4/20 0.60
▸ HCAR2 Q8TDS4 2/20 0.59
▸ CA12 O43570 1/20 0.59
▸ AKR1B10 O60218 1/20 0.59
▸ CA1 P00915 1/20 0.59
▸ CA2 P00918 1/20 0.59
▸ ESR1 P03372 1/20 0.59
▸ CA3 P07451 1/20 0.59
▸ PKM P14618 1/20 0.59
▸ TYR P14679 1/20 0.59
▸ AKR1B1 P15121 1/20 0.59
▸ CA4 P22748 1/20 0.59
▸ CA6 P23280 1/20 0.59
▸ DPP4 P27487 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL992033 1.00 ALDH1A1 (0.67) ALDH1A1MAPTLMNAL3MBTL1FFAR1
Hydrochloric Acid SCHEMBL6818309 0.98 ALDH1A1 (0.65) ALDH1A1MAPTLMNAL3MBTL1FFAR1
Hydrochloric Acid SCHEMBL27894460 0.98 ALDH1A1 (0.65) ALDH1A1MAPTLMNAL3MBTL1FFAR1
SCHEMBL9421253 0.94 HDAC2 (0.71) ALDH1A1MAPTLMNAL3MBTL1FFAR1
SCHEMBL9365577 0.91 ALDH1A1 (0.58) ALDH1A1MAPTLMNAL3MBTL1FFAR1
SCHEMBL9365579 0.91 ALDH1A1 (0.58) ALDH1A1MAPTLMNAL3MBTL1FFAR1
4-Methoxycinnamic Acid SCHEMBL8346565 0.87 THRB (0.76) ALDH1A1MAPTLMNAL3MBTL1FFAR1
4-Methoxycinnamic Acid SCHEMBL8346567 0.87 THRB (0.76) ALDH1A1MAPTLMNAL3MBTL1FFAR1
Diethylamine SCHEMBL10944799 0.87 HDAC2 (0.54) ALDH1A1MAPTLMNAL3MBTL1FFAR1
SCHEMBL9361409 0.87 HDAC2 (0.65) ALDH1A1MAPTLMNAL3MBTL1FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 264 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12365830-B2 Ligand-exchangeable janus nanoparticles and methods of making the same ALLIANCE FOR SUSTAINABLE ENERGY, LLC (US) 2025-07-22 — — US claimed
CN-118812422-A MALDI-FT-ICR mass spectrometry probe for single-chain sphingolipid detection and preparation method and application method thereof 国科大杭州高等研究院 2024-10-22 — — CN claimed
US-20220259490-A1 LIGAND-EXCHANGEABLE JANUS NANOPARTICLES AND METHODS OF MAKING THE SAME Alliance for Energy Innovation, LLC 2022-08-18 — — US claimed
WO-2020252075-A1 LIGAND-EXCHANGEABLE JANUS NANOPARTICLES AND METHODS OF MAKING THE SAME ALLIANCE FOR SUSTAINABLE ENERGY, LLC (US) 2020-12-17 — — WO claimed
US-10544168-B2 Ligand-exchangeable nanoparticles and methods of making the same ALLIANCE FOR SUSTAINABLE ENERGY, LLC (US) 2020-01-28 — — US claimed
EP-3208301-B1 RESIN COMPOSITION AND OPTICAL COMPENSATION FILM USING SAME TOSOH CORP (JP) 2019-04-03 — — EP claimed
US-20170362255-A1 LIGAND-EXCHANGEABLE NANOPARTICLES AND METHODS OF MAKING THE SAME Alliance for Energy Innovation, LLC 2017-12-21 — — US claimed
EP-0587050-B1 Process for the preparation of an aromatic group substituted olefins from chloroaromatics HOECHST AG (DE) 1996-03-13 — — EP claimed
US-4758312-A Adding colorless electrochemically active compound having positive reduction potential NALCO CHEMICAL COMPANY (US) 1988-07-19 — — US claimed
US-12365830-B2 Ligand-exchangeable janus nanoparticles and methods of making the same ALLIANCE FOR SUSTAINABLE ENERGY, LLC (US) 2025-07-22 — — US disclosed
CN-120136796-A Alpha, beta unsaturated ketone derivative and preparation method and application thereof 河南大学 2025-06-13 — — CN disclosed
US-20250034121-A1 COMPOUNDS AND THEIR USES AS GPR183 INHIBITORS NANJING IMMUNOPHAGE BIOMEDICAL CO., LTD. (CN) 2025-01-30 — — US disclosed
CN-115677610-B Benzoxazolinone derivative, preparation method and application thereof 安徽中医药大学 2024-12-06 — — CN disclosed
CN-118697737-A Application of piperlonguminine analogue compound in preparation of medicines for treating cervical cancer and/or liver cancer 赣南医学院第一附属医院 2024-09-27 — — CN disclosed
US-4244966-A 1,3-Dihydro-3-(2-hydroxy-, 2-bromo- or 2-chloroethyl)-2H-isoindol-1-one derivatives AMERICAN HOME PRODUCTS CORPORATION (US) 1981-01-13 — — US disclosed
US-4238506-A SECONDARY OR TERTIARY AMIDE-SUBSTITUTED BOEHRINGER MANNHEIM GMBH (DE) 1980-12-09 — — US disclosed
US-4113871-A HYPOGLYCEMICALLY AND HYPOLIPIDEMICALLY ACTIVE DERIVATIVES OF PHENYL-ALKANE-CARBOXYLIC ACIDS BOEHRINGER MANNHEIM GMBH (DE) 1978-09-12 — — US disclosed
US-4058475-A NEMATIC DAI NIPPON TORYO CO., LTD. (JA) 1977-11-15 — — US disclosed
US-3962219-A DISTYRYL-BENZOBISOXAZOLES BAYER AKTIENGESELLSCHAFT (DT) 1976-06-08 — — US disclosed
US-3931168-A Cinnamamidohydantoins MORTON-NORWICH PRODUCTS, INC. (US) 1976-01-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10544168-B2 Ligand-exchangeable nanoparticles and methods of making the same CA6, CA13, EPCAM ALDH1A1 137/4885MAPT 2354/4885LMNA 1880/4885
US-20170362255-A1 LIGAND-EXCHANGEABLE NANOPARTICLES AND METHODS OF MAKING THE SAME CA6, CA13, EPCAM ALDH1A1 137/4885MAPT 2354/4885LMNA 1880/4885
US-20250034121-A1 COMPOUNDS AND THEIR USES AS GPR183 INHIBITORS GPR183, GPR180, GPR65 ALDH1A1 4198/4885MAPT 3530/4885LMNA 3500/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.