Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8091546 | 0.85 | PDE6D (0.42) | HSP90AA1HSP90AB1HPGDALDH1A1GAA | |
| SCHEMBL7569237 | 0.79 | HTT (0.54) | TSHRALDH1A1NPC1CYP1A2CYP2D6 | |
| SCHEMBL8091535 | 0.76 | HSP90AA1 (0.53) | HSP90AA1HSP90AB1TSHRHPGDALDH1A1 | |
| SCHEMBL8091542 | 0.75 | KDM4E (0.39) | HSP90AA1HSP90AB1ALDH1A1GAAPOLB | |
| SCHEMBL7568209 | 0.72 | HDAC3 (0.50) | HSP90AA1HSP90AB1TSHRHPGDALDH1A1 | |
| SCHEMBL8090021 | 0.72 | PDK1 (0.53) | HSP90AA1HSP90AB1TSHRHPGDALDH1A1 | |
| SCHEMBL7572903 | 0.69 | MAPT (0.56) | NPC1CYP1A2RAB9A | |
| SCHEMBL7404896 | 0.66 | TERT (0.58) | ALDH1A1CYP2D6SMN1; SMN2GAAPOLB | |
| SCHEMBL13236606 | 0.65 | HPGD (0.49) | HSP90AA1HSP90AB1TSHRHPGDALDH1A1 | |
| SCHEMBL23420051 | 0.65 | TP53 (0.55) | TSHRALDH1A1HTTSMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807628-B1 | Aromatic compound and pharmaceutical composition | KUREHA CHEMICAL IND CO LTD (JP) | 2000-12-20 | — | — | EP | disclosed |
| EP-0807628-A1 | Aromatic compound and pharmaceutical composition | Kureha Chemical Industry Co., Ltd. (JP) | 1997-11-19 | — | — | EP | disclosed |