Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 8/20 | 0.61 |
| ▸ | TOP2B | Q02880 | 7/20 | 0.61 |
| ▸ | KDM1A | O60341 | 5/20 | 0.44 |
| ▸ | CTSD | P07339 | 2/20 | 0.43 |
| ▸ | BLK | P51451 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7568578 | 0.90 | TOP2A (0.61) | TOP2ATOP2BKDM1ACTSD | |
| SCHEMBL7567330 | 0.89 | TOP2A (0.73) | TOP2ATOP2BKDM1AKDM4EGLA | |
| SCHEMBL7564074 | 0.87 | TOP2A (0.66) | TOP2ATOP2BKDM1ABLKBTK | |
| SCHEMBL7564525 | 0.87 | TOP2A (0.61) | TOP2ATOP2BKDM1APOLBPARP1 | |
| SCHEMBL7561269 | 0.86 | TOP2A (0.66) | TOP2ATOP2BKDM1AKDM4EGLA | |
| SCHEMBL7563689 | 0.82 | TOP2A (0.77) | TOP2ATOP2BKDM1AKDM4EGLA | |
| SCHEMBL7561273 | 0.82 | TOP2A (0.70) | TOP2ATOP2BBLKBTKKDM4E | |
| SCHEMBL7568574 | 0.81 | TOP2A (0.73) | TOP2ATOP2BKDM1AKDM4EGLA | |
| SCHEMBL3983138 | 0.81 | TOP2A (0.53) | TOP2ATOP2BKDM1ACTSD | |
| SCHEMBL3981533 | 0.80 | TOP2A (0.80) | TOP2ATOP2BKDM1AKDM4EGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020111491-A1 | 9-aminoacridine derivatives and process for the preparation thereof | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2002-08-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020111491-A1 | 9-aminoacridine derivatives and process for the preparation thereof | ALKBH1, ADCY9, CCR9 | TOP2A 1105/4885TOP2B 841/4885KDM1A 1325/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.