Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6588396 | 0.84 | ALDH1A1 (0.34) | ALDH1A1POLBKMT2ATLR8 | |
| SCHEMBL9684184 | 0.78 | DUT (0.31) | ALDH1A1POLBKMT2A | |
| SCHEMBL2513945 | 0.76 | KMT2A (0.53) | ALDH1A1POLBKMT2A | |
| SCHEMBL2061624 | 0.74 | ALDH1A1 (0.35) | ALDH1A1POLBKMT2ATLR8 | |
| SCHEMBL13099877 | 0.74 | TLR8 (0.58) | ALDH1A1POLBKMT2ATLR8 | |
| Hydrochloric Acid SCHEMBL3304863 | 0.74 | ALDH1A1 (0.35) | ALDH1A1POLBKMT2ATLR8 | |
| SCHEMBL28470170 | 0.74 | KCNH2 (0.36) | ALDH1A1POLBKMT2ATLR8 | |
| SCHEMBL14451168 | 0.73 | SMN1; SMN2 (0.38) | ALDH1A1POLBKMT2ATLR8 | |
| SCHEMBL5093089 | 0.69 | LPO (0.43) | ALDH1A1POLBKMT2ATLR8 | |
| SCHEMBL3065697 | 0.67 | ALDH1A1 (0.40) | ALDH1A1POLBKMT2ATLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020019527-A1 | Substituted phenyl farnesyltransferase inhibitors | ABBOTT LABORATORIES | 2002-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020019527-A1 | Substituted phenyl farnesyltransferase inhibitors | FNTA, FNTB, SLC10A1 | ALDH1A1 385/4885POLB 3455/4885KMT2A 3687/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.