Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.51 |
| ▸ | CCR2 | P41597 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | CDK1 | P06493 | 1/20 | 0.50 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.50 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.50 |
| ▸ | CDK2 | P24941 | 1/20 | 0.50 |
| ▸ | CDK7 | P50613 | 1/20 | 0.50 |
| ▸ | CCNH | P51946 | 1/20 | 0.50 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.50 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7572541 | 0.92 | FFAR1 (0.62) | MEN1GAAKMT2AHSD17B2CCR2 | |
| SCHEMBL7572611 | 0.87 | CCR2 (0.55) | MEN1GAAKMT2AHSD17B2CCR2 | |
| SCHEMBL7571635 | 0.85 | FFAR1 (0.66) | MEN1GAAKMT2AHSD17B2CCR2 | |
| SCHEMBL10583133 | 0.82 | HSD17B2 (0.58) | MEN1GAAKMT2AHSD17B2CCR2 | |
| SCHEMBL7572737 | 0.81 | MCL1 (0.60) | MEN1GAAKMT2ACCR2LMNA | |
| SCHEMBL7577554 | 0.81 | MEN1 (0.55) | MEN1GAAKMT2AHSD17B2CCR2 | |
| SCHEMBL7594309 | 0.80 | KMT2A (0.63) | MEN1GAAKMT2AHSD17B2CCR2 | |
| SCHEMBL7592771 | 0.80 | MEN1 (0.74) | MEN1GAAKMT2AHSD17B2CCR2 | |
| SCHEMBL7568254 | 0.78 | MEN1 (0.57) | MEN1GAAKMT2AHSD17B2CCR2 | |
| SCHEMBL7578587 | 0.78 | MEN1 (0.52) | MEN1GAAKMT2AHSD17B2CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |