Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.62 |
| ▸ | CDK1 | P06493 | 1/20 | 0.62 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.62 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.62 |
| ▸ | CDK2 | P24941 | 1/20 | 0.62 |
| ▸ | CDK7 | P50613 | 1/20 | 0.62 |
| ▸ | CCNH | P51946 | 1/20 | 0.62 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.62 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | XBP1 | P17861 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7569677 | 0.92 | MEN1 (0.52) | FFAR1CDK1CCNB1CCNA2CDK2 | |
| SCHEMBL7571635 | 0.91 | FFAR1 (0.66) | FFAR1CDK1CCNB1CCNA2CDK2 | |
| SCHEMBL5956006 | 0.84 | KEAP1 (0.58) | FFAR4MEN1KMT2ALMNATP53 | |
| SCHEMBL7570517 | 0.82 | CYP2C9 (0.61) | FFAR1CDK1CCNB1CCNA2CDK2 | |
| SCHEMBL7591285 | 0.82 | SLC40A1 (0.59) | MEN1KMT2ALMNAMAPTHTT | |
| SCHEMBL10583133 | 0.81 | HSD17B2 (0.58) | FFAR1CDK1CCNB1CCNA2CDK2 | |
| SCHEMBL7572737 | 0.81 | MCL1 (0.60) | MEN1KMT2ALMNANPSR1GAA | |
| SCHEMBL7577554 | 0.80 | MEN1 (0.55) | FFAR4MEN1KMT2ALMNANPSR1 | |
| SCHEMBL7578587 | 0.80 | MEN1 (0.52) | MEN1KMT2ALMNANPSR1MAPT | |
| SCHEMBL7572596 | 0.79 | MEN1 (0.67) | FFAR1CDK1CCNB1CCNA2CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |