Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.50 |
| ▸ | CLK1 | P49759 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3624463 | 0.84 | ALDH1A1 (0.64) | MEN1KMT2ASLC40A1CA2ALDH1A1 | |
| SCHEMBL7577554 | 0.81 | MEN1 (0.55) | MEN1GAAKMT2ALMNANPSR1 | |
| SCHEMBL7568328 | 0.81 | GAA (0.50) | MEN1GAAKMT2ALMNANPSR1 | |
| SCHEMBL7572541 | 0.80 | FFAR1 (0.62) | MEN1GAAKMT2ALMNANPSR1 | |
| SCHEMBL3624288 | 0.78 | CCR2 (0.50) | MEN1KMT2ALMNAALDH1A1MAPT | |
| SCHEMBL7569677 | 0.78 | MEN1 (0.52) | MEN1GAAKMT2ALMNANPSR1 | |
| SCHEMBL7594309 | 0.77 | KMT2A (0.63) | MEN1GAAKMT2ALMNANPSR1 | |
| SCHEMBL7592771 | 0.77 | MEN1 (0.74) | MEN1GAAKMT2ALMNANPSR1 | |
| SCHEMBL7612721 | 0.76 | CRHBP (0.70) | MEN1GAAKMT2ALMNANPSR1 | |
| SCHEMBL7572806 | 0.76 | NR3C1 (0.69) | MEN1GAAKMT2ALMNACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |