Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7568049 | 0.80 | HSP90AB1 (0.55) | KMT2AHSP90AB1TSHRMAPTLMNA | |
| SCHEMBL8084685 | 0.79 | KMT2A (0.49) | KMT2AHSP90AB1TSHRMAPTLMNA | |
| SCHEMBL14163375 | 0.76 | KMT2A (0.42) | KMT2AHSP90AB1TSHRMAPTLMNA | |
| SCHEMBL8086252 | 0.76 | KMT2A (0.46) | KMT2AHSP90AB1TSHRMAPTHIF1A | |
| SCHEMBL763785 | 0.71 | HRH4 (0.37) | KMT2AHSP90AB1MAPTMEN1NPC1 | |
| SCHEMBL7569734 | 0.71 | MEN1 (0.53) | KMT2AMAPTLMNAMEN1NPC1 | |
| SCHEMBL17400454 | 0.70 | LMNA (0.43) | KMT2AHSP90AB1TSHRMAPTLMNA | |
| SCHEMBL96485 | 0.68 | — | — | |
| SCHEMBL754084 | 0.67 | KMT2A (0.40) | KMT2AMAPTMEN1NPC1L3MBTL1 | |
| SCHEMBL6360346 | 0.66 | MAPT (0.46) | KMT2AMAPTMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077981-B1 | NOVEL CEPHALOSPORIN COMPOUNDS, PROCESSES FOR PREPARATION THEREOF AND ANTIMICROBIAL COMPOSITIONS CONTAINING THE SAME | LG CHEMICAL LTD (KR) | 2002-08-07 | — | — | EP | disclosed |