Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 14/20 | 1.00 |
| ▸ | CCKBR | P32239 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7569576 | 0.86 | P2RX7 (1.00) | P2RX7CA2 | |
| SCHEMBL19354785 | 0.84 | P2RX7 (0.72) | P2RX7CA2 | |
| SCHEMBL3454922 | 0.83 | P2RX7 (1.00) | P2RX7CA2 | |
| SCHEMBL7571956 | 0.79 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL7571523 | 0.78 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL7571588 | 0.78 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL19321961 | 0.77 | P2RX7 (0.63) | P2RX7CA2 | |
| SCHEMBL6362496 | 0.76 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL6054751 | 0.76 | P2RX7 (0.70) | P2RX7TP53CA2 | |
| SCHEMBL17483924 | 0.76 | P2RX7 (0.75) | P2RX7CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1036059-B1 | ADAMANTANE DERIVATIVES | ASTRAZENECA UK LTD (GB) | 2002-09-18 | — | — | EP | claimed |
| EP-1036059-B1 | ADAMANTANE DERIVATIVES | ASTRAZENECA UK LTD (GB) | 2002-09-18 | — | — | EP | disclosed |