Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.40 |
| ▸ | RAB9A | P51151 | 6/20 | 0.40 |
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | CCR1 | P32246 | 3/20 | 0.39 |
| ▸ | CCR5 | P51681 | 3/20 | 0.39 |
| ▸ | CCR8 | P51685 | 3/20 | 0.39 |
| ▸ | METAP1 | P53582 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14783132 | 0.80 | KDM4E (0.45) | SMN1; SMN2RAB9ALMNANPC1HPGD | |
| SCHEMBL7569351 | 0.79 | TGFBR1 (0.45) | TGFBR1SMN1; SMN2RAB9ALMNANPC1 | |
| SCHEMBL1033552 | 0.76 | KDM4E (0.48) | SMN1; SMN2RAB9ALMNANPC1HPGD | |
| SCHEMBL5796609 | 0.75 | KDM4E (0.39) | TGFBR1SMN1; SMN2RAB9ALMNANPC1 | |
| SCHEMBL7265635 | 0.73 | KDM4E (0.59) | SMN1; SMN2RAB9ALMNANPC1HPGD | |
| SCHEMBL7571214 | 0.72 | KDM4E (0.43) | TGFBR1SMN1; SMN2RAB9ALMNANPC1 | |
| SCHEMBL14782994 | 0.72 | KDM4E (0.39) | TGFBR1SMN1; SMN2RAB9ALMNANPC1 | |
| SCHEMBL6207069 | 0.70 | CYP2A6 (0.43) | RAB9ALMNANPC1HPGDCASP3 | |
| SCHEMBL14782863 | 0.70 | KDM4E (0.41) | TGFBR1SMN1; SMN2RAB9ALMNANPC1 | |
| SCHEMBL3363096 | 0.69 | KDM4E (0.48) | SMN1; SMN2RAB9ALMNANPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002089799-A2 | USE OF DIHYDROPYRAZOLES TO INCREASE ERYTHROPOIETIN AND VASCULARI ZATION | THE PROCTER & GAMBLE COMPANY (US) | 2002-11-14 | — | — | WO | disclosed |