SCHEMBL7569351

SCHEMBL7569351

[c]1cccc(-c2ccccc2)c1-c1ccccn1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 2/20 0.45
KDM4E B2RXH2 6/20 0.43
LMNA P02545 6/20 0.43
CCR1 P32246 3/20 0.43
CCR5 P51681 3/20 0.43
CCR8 P51685 3/20 0.43
CYP1A2 P05177 1/20 0.43
POLB P06746 1/20 0.43
METAP1 P53582 1/20 0.43
BLM P54132 1/20 0.43
HIF1A Q16665 1/20 0.43
DOHH Q9BU89 1/20 0.43
P4HTM Q9NXG6 1/20 0.43
CHRNB2 P17787 1/20 0.42
CHRNB4 P30926 1/20 0.42
CHRNA3 P32297 1/20 0.42
CHRNA4 P43681 1/20 0.42
CYP2A6 P11509 1/20 0.41
KDR P35968 1/20 0.40
SMN1; SMN2 Q16637 6/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3363096 0.87 KDM4E (0.48) KDM4ELMNACCR1CCR5CCR8
SCHEMBL7571214 0.86 KDM4E (0.43) TGFBR1KDM4ELMNACCR1CCR5
SCHEMBL7570520 0.79 TGFBR1 (0.42) TGFBR1KDM4ELMNACCR1CCR5
SCHEMBL7265635 0.77 KDM4E (0.59) KDM4ELMNACCR1CCR5CCR8
SCHEMBL185890 0.77 ALDH1A1 (0.41) CYP2A6HPGDTDP1ALDH1A1HSD17B10
SCHEMBL14783069 0.76 CYP2A6 (0.58) TGFBR1KDM4ELMNACCR1CCR5
SCHEMBL4252928 0.76 KDM4E (0.48) KDM4ELMNACCR1CCR5CCR8
SCHEMBL5063039 0.75 TGFBR1 (0.45) TGFBR1KDM4ELMNACCR1CCR5
SCHEMBL3364759 0.75 KDM4E (0.56) TGFBR1KDM4ELMNACCR1CCR5
SCHEMBL9656806 0.75 KDM4E (0.46) KDM4ELMNACCR1CCR5CCR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109311844-B Triazine compound, method for producing same, and organic electroluminescent element containing same as constituent component 东曹株式会社 2021-07-20 CN disclosed
WO-2002089799-A2 USE OF DIHYDROPYRAZOLES TO INCREASE ERYTHROPOIETIN AND VASCULARI ZATION THE PROCTER & GAMBLE COMPANY (US) 2002-11-14 WO disclosed