Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.39 |
| ▸ | LMNA | P02545 | 6/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.39 |
| ▸ | CCR1 | P32246 | 2/20 | 0.39 |
| ▸ | CCR5 | P51681 | 2/20 | 0.39 |
| ▸ | CCR8 | P51685 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.39 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.36 |
| ▸ | NPC1 | O15118 | 6/20 | 0.36 |
| ▸ | TP53 | P04637 | 6/20 | 0.36 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | PKM | P14618 | 3/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7571214 | 0.79 | KDM4E (0.43) | KDM4ELMNAHIF1ACCR1CCR5 | |
| SCHEMBL1033552 | 0.76 | KDM4E (0.48) | KDM4ELMNAHIF1ACCR1CCR5 | |
| SCHEMBL7570520 | 0.75 | TGFBR1 (0.42) | KDM4ELMNAHIF1ACCR1CCR5 | |
| SCHEMBL5797476 | 0.75 | CYP2A6 (0.44) | CYP1A2CYP2A6NPY5RALDH1A1 | |
| SCHEMBL13834138 | 0.75 | PDCD1 (0.52) | KDM4ELMNAHIF1ACCR1CCR5 | |
| SCHEMBL14782863 | 0.73 | KDM4E (0.41) | KDM4ELMNAHIF1ACCR1CCR5 | |
| SCHEMBL7569351 | 0.72 | TGFBR1 (0.45) | KDM4ELMNAHIF1ACCR1CCR5 | |
| SCHEMBL4775110 | 0.72 | RAB9A (0.37) | KDM4ELMNAHIF1ACCR1CCR5 | |
| SCHEMBL19592547 | 0.72 | KDM4E (0.56) | KDM4ELMNAHIF1ACCR1CCR5 | |
| SCHEMBL21742644 | 0.71 | TGFBR1 (0.47) | KDM4ELMNAHIF1ACCR1CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006033995-A2 | THIAZOLIDIN-4-ONES HAVING ANTI-HEPATITIS B ACTIVITY | VALEANT RESEARCH AND DEVELOPMENT (US) | 2006-03-30 | — | — | WO | disclosed |