SCHEMBL7570626

SCHEMBL7570626

O=S(=O)(Nc1cccc(Cl)c1Cl)c1ccc(Cl)cc1

nearest known ligand 0.71

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.61
CYP19A1 P11511 1/20 0.57
MEN1 O00255 1/20 0.57
TSHR P16473 1/20 0.57
KMT2A Q03164 1/20 0.57
SLC40A1 Q9NP59 1/20 0.56
KDM4E B2RXH2 1/20 0.56
LMNA P02545 1/20 0.56
GAA P10253 1/20 0.56
HTT P42858 1/20 0.56
CES1 P23141 1/20 0.55
CCR2 P41597 3/20 0.53
HKDC1 Q2TB90 1/20 0.51
PTGES2 Q9H7Z7 1/20 0.50
ERBB2 P04626 1/20 0.50
HSP90AA1 P07900 1/20 0.50
HSP90AB1 P08238 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7569069 0.88 TSHR (0.58) ALDH1A1MEN1TSHRKMT2ASLC40A1
SCHEMBL7570382 0.86 TSHR (0.75) ALDH1A1CYP19A1MEN1TSHRKMT2A
SCHEMBL29498595 0.83 PGR (0.59) TSHRSLC40A1KDM4ELMNAPTGES2
SCHEMBL19994906 0.80 PTGES2 (0.51) MEN1TSHRKMT2AKDM4ECCR2
SCHEMBL29498580 0.80 PTGES2 (0.51) MEN1TSHRKMT2AKDM4ECCR2
SCHEMBL3785727 0.78 RECQL (0.62) ALDH1A1MEN1TSHRKMT2ASLC40A1
SCHEMBL27183202 0.77 MEN1 (0.46) ALDH1A1MEN1TSHRKMT2ASLC40A1
SCHEMBL1471878 0.76 PTGES2 (0.61) ALDH1A1KMT2AKDM4ELMNAGAA
SCHEMBL4184006 0.76 ALDH1A1 (0.66) ALDH1A1CYP19A1MEN1TSHRKMT2A
SCHEMBL10143537 0.76 ALDH1A1 (0.71) ALDH1A1CYP19A1CES1CCR2HKDC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0104353-B1 HEAT SENSITIVE RECORD MATERIAL HODOGAYA CHEMICAL CO., LTD. (JP) 1987-10-28 EP claimed
US-4482905-A FLUORAN, BENZENESULFONAMIDE, ACID, BINDER HODOGAYA CHEMICAL CO., LTD. (JP) 1984-11-13 US claimed
EP-0104353-A2 Heat sensitive record material HODOGAYA CHEMICAL CO., LTD. (JP) 1984-04-04 EP claimed
WO-2002078970-A1 HEAT SENSITIVE RECORDING MATERIAL CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2002-10-10 WO disclosed