SCHEMBL7570382

SCHEMBL7570382

O=S(=O)(Nc1ccccc1Cl)c1ccc(Cl)cc1

nearest known ligand 0.82

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.75
MEN1 O00255 1/20 0.75
KMT2A Q03164 1/20 0.75
ALDH1A1 P00352 2/20 0.70
GPR27 Q9NS67 1/20 0.60
PKM P14618 1/20 0.58
CES1 P23141 1/20 0.58
HKDC1 Q2TB90 1/20 0.58
ERBB2 P04626 1/20 0.57
HSP90AA1 P07900 1/20 0.57
HSP90AB1 P08238 1/20 0.57
PTGES2 Q9H7Z7 1/20 0.56
CYP19A1 P11511 1/20 0.56
GRM4 Q14833 1/20 0.56
CCR2 P41597 1/20 0.55
KDM4E B2RXH2 2/20 0.55
SLC40A1 Q9NP59 1/20 0.55
LMNA P02545 1/20 0.55
GAA P10253 1/20 0.55
HTT P42858 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3791578 0.89 TSHR (0.74) TSHRMEN1KMT2AALDH1A1PKM
SCHEMBL1592846 0.86 TSHR (0.71) TSHRMEN1KMT2AALDH1A1GPR27
SCHEMBL7592222 0.86 TSHR (0.71) TSHRMEN1KMT2AALDH1A1PKM
SCHEMBL7570626 0.86 ALDH1A1 (0.61) TSHRMEN1KMT2AALDH1A1CES1
SCHEMBL1970942 0.86 KMT2A (0.71) TSHRMEN1KMT2AALDH1A1PKM
SCHEMBL30557370 0.86 TSHR (0.71) TSHRMEN1KMT2AALDH1A1PKM
SCHEMBL29561469 0.82 PKM (0.64) TSHRMEN1KMT2AALDH1A1GPR27
SCHEMBL10143537 0.82 ALDH1A1 (0.71) ALDH1A1CES1HKDC1PTGES2CYP19A1
SCHEMBL4184006 0.82 ALDH1A1 (0.66) TSHRMEN1KMT2AALDH1A1CES1
SCHEMBL30737499 0.82 ALDH1A1 (0.66) TSHRMEN1KMT2AALDH1A1CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0104353-B1 HEAT SENSITIVE RECORD MATERIAL HODOGAYA CHEMICAL CO., LTD. (JP) 1987-10-28 EP claimed
US-4482905-A FLUORAN, BENZENESULFONAMIDE, ACID, BINDER HODOGAYA CHEMICAL CO., LTD. (JP) 1984-11-13 US claimed
EP-0104353-A2 Heat sensitive record material HODOGAYA CHEMICAL CO., LTD. (JP) 1984-04-04 EP claimed
WO-2002078970-A1 HEAT SENSITIVE RECORDING MATERIAL CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2002-10-10 WO disclosed