Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7782583 | 0.93 | RAB9A (0.39) | RAB9ASLC6A4MEN1POLBKMT2A | |
| SCHEMBL7868306 | 0.90 | — | — | |
| SCHEMBL7844834 | 0.85 | GCGR (0.33) | RAB9ASLC6A4HTR2AKCNH2LMNA | |
| SCHEMBL7717493 | 0.77 | KDM4E (0.39) | HTR2A | |
| SCHEMBL7570657 | 0.76 | RAB9A (0.39) | RAB9ASLC6A4MEN1POLBKMT2A | |
| SCHEMBL6811369 | 0.74 | SLC6A4 (0.45) | RAB9ASLC6A4MEN1POLBKMT2A | |
| SCHEMBL6811367 | 0.74 | SLC6A4 (0.45) | RAB9ASLC6A4MEN1POLBKMT2A | |
| SCHEMBL7868617 | 0.74 | S1PR1 (0.34) | RAB9ASLC6A4MEN1KMT2A | |
| SCHEMBL7782578 | 0.73 | RAB9A (0.45) | RAB9ASLC6A4MEN1POLBKMT2A | |
| SCHEMBL7575131 | 0.73 | AKR1B1 (0.36) | SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1144399-A3 | HETEROCYCLIC CARBOXAMIDE-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES CONTAINING A SUBSTITUTED PHENYLENEDIAMINE GROUP | Wyeth (US) | 2002-09-11 | — | — | EP | disclosed |
| EP-1144399-A2 | HETEROCYCLIC CARBOXAMIDE-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES CONTAINING A SUBSTITUTED PHENYLENEDIAMINE GROUP | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000034261-A2 | HETEROCYCLIC CARBOXAMIDE-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES CONTAINING A SUBSTITUTED PHENYLENEDIAMINE GROUP | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-06-15 | — | — | WO | disclosed |