Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 2/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.34 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.31 |
| ▸ | PPARG | P37231 | 2/20 | 0.31 |
| ▸ | GPR183 | P32249 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7784388 | 0.92 | NPFFR2 (0.37) | S1PR1S1PR3IDO1NPFFR2PPARG | |
| SCHEMBL7866868 | 0.84 | IDO1 (0.31) | IDO1EPHX2PPARG | |
| SCHEMBL7784385 | 0.79 | NPFFR2 (0.45) | NPFFR2MEN1KMT2ASLC6A4RAB9A | |
| SCHEMBL7868613 | 0.79 | NPFFR2 (0.38) | NPFFR2MEN1KMT2ARAB9A | |
| SCHEMBL7845167 | 0.78 | GPR183 (0.33) | GPR183MEN1NPC1KMT2ASLC6A2 | |
| SCHEMBL7844834 | 0.78 | GCGR (0.33) | S1PR3SLC6A4RAB9A | |
| SCHEMBL7782583 | 0.77 | RAB9A (0.39) | PPARGMEN1NPC1KMT2ASLC6A4 | |
| SCHEMBL7778528 | 0.77 | — | — | |
| SCHEMBL7570658 | 0.74 | RAB9A (0.34) | MEN1KMT2ASLC6A4RAB9A | |
| SCHEMBL6816713 | 0.73 | KIF11 (0.49) | NPFFR2PPARGMEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140913-A1 | THIOUREA INHIBITORS OF HERPES VIRUSES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000034269-A1 | THIOUREA INHIBITORS OF HERPES VIRUSES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-06-15 | — | — | WO | disclosed |