Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 5/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chlorobenzene SCHEMBL27889729 | 0.84 | POLB (0.46) | KLK7SLC6A4SLC6A3POLBALDH1A1 | |
| Biphenyl SCHEMBL27695862 | 0.83 | POLB (0.48) | POLBALDH1A1LMNAKDM4ETSHR | |
| Benzene SCHEMBL28075751 | 0.82 | TSHR (0.50) | POLBALDH1A1LMNAKDM4ETSHR | |
| Chlorobenzene SCHEMBL27773693 | 0.82 | POLB (0.44) | KLK7SLC6A4SLC6A3POLBALDH1A1 | |
| Chlorobenzene SCHEMBL4075795 | 0.82 | POLB (0.44) | KLK7SLC6A4SLC6A3POLBALDH1A1 | |
| Dimethyl Succinate SCHEMBL28197313 | 0.82 | ALDH1A1 (0.51) | POLBALDH1A1LMNAKDM4ETSHR | |
| Chlorobenzene SCHEMBL28362949 | 0.81 | KMT2A (0.47) | POLBALDH1A1LMNAKDM4ETSHR | |
| Chlorobenzene SCHEMBL27856994 | 0.81 | POLB (0.43) | KLK7SLC6A4SLC6A3POLBALDH1A1 | |
| Chlorobenzene SCHEMBL27389658 | 0.81 | CYP4F2 (0.47) | KLK7ALDH1A1LMNATSHRMAPT | |
| Bromobenzene SCHEMBL28192537 | 0.80 | HPGD (0.46) | SLC6A3POLBALDH1A1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0746551-B1 | OPTICALLY PURE 4-ARYL-2-HYDROXYTETRONIC ACIDS | UNIV OHIO STATE RES FOUND (US) | 2002-09-04 | — | — | EP | disclosed |
| EP-0746551-A1 | OPTICALLY PURE 4-ARYL-2-HYDROXYTETRONIC ACIDS | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1996-12-11 | — | — | EP | disclosed |
| US-5504108-A | ANTIAGGLOMERANTS, ANTIARTHRITIC AGENTS | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1996-04-02 | — | — | US | disclosed |
| WO-1995023139-A1 | OPTICALLY PURE 4-ARYL-2-HYDROXYTETRONIC ACIDS | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1995-08-31 | — | — | WO | disclosed |
| US-5399721-A | Anticoagulant; prepared from aldehyde | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1995-03-21 | — | — | US | disclosed |