Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 6/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 6/20 | 0.39 |
| ▸ | RORC | P51449 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | IGF1R | P08069 | 1/20 | 0.36 |
| ▸ | PTPRB | P23467 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7094898 | 0.87 | ADRB3 (0.41) | ALDH1A1ADRB1ADRB3RORCNPC1 | |
| SCHEMBL7091978 | 0.84 | ALDH1A1 (0.44) | NAMPTALDH1A1SIGMAR1ADRB1ADRB3 | |
| SCHEMBL7570714 | 0.82 | ADRB3 (0.49) | NAMPTALDH1A1SIGMAR1ADRB1ADRB3 | |
| SCHEMBL25832689 | 0.80 | NAMPT (0.49) | NAMPTSIGMAR1NPC1MAPTRAB9A | |
| SCHEMBL7094897 | 0.74 | ADRB3 (0.52) | ADRB1ADRB3MAPT | |
| SCHEMBL7091450 | 0.74 | ADRB3 (0.74) | ADRB1ADRB3 | |
| SCHEMBL7091377 | 0.74 | ADRB3 (0.49) | NAMPTALDH1A1SIGMAR1ADRB1ADRB3 | |
| SCHEMBL7094990 | 0.73 | ADRB3 (0.63) | ADRB1ADRB3 | |
| SCHEMBL7570375 | 0.73 | ADRB3 (0.67) | ADRB1ADRB3 | |
| SCHEMBL7092285 | 0.72 | ADRB3 (0.64) | ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020028832-A1 | Heterocyclic beta-3 adrenergic receptor agonists | AMERICAN HOME PRODUCTS CORPORATION (US) | 2002-03-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020028832-A1 | Heterocyclic beta-3 adrenergic receptor agonists | ADRB1, ADRB3, ADRB2 | NAMPT 2909/4885ALDH1A1 524/4885SIGMAR1 125/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.